UV protection and insecticidal activity of microencapsulated Vip3Ag4 protein in Bacillus megaterium

In this study, secretable Vip3Ag4 protein was encapsulated in Bacillus megaterium and used for quantitative bioassays, in order to determine the UV photoprotective capacity of the cell, for preventing inactivation of the insecticidal activity of the protein. The non-encapsulated and purified protein...

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Detalles Bibliográficos
Autores: Palma Dovis, Leopoldo, Ruiz de Escudero Fuentemilla, Íñigo, Mañeru Oria, Francisco Javier, Berry, Colin, Caballero Murillo, Primitivo
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2024
País:España
Institución:Universidad Pública de Navarra
Repositorio:Academica-e. Repositorio Institucional de la Universidad Pública de Navarra
OAI Identifier:oai:academica-e.unavarra.es:2454/52301
Acceso en línea:https://hdl.handle.net/2454/52301
Access Level:acceso abierto
Palabra clave:Bacillus megaterium
Bacillus thuringiensis
Bioinsecticide formulations
Biological control
Insect pests
Microencapsulation
Priestia megaterium
Vip3 proteins
Descripción
Sumario:In this study, secretable Vip3Ag4 protein was encapsulated in Bacillus megaterium and used for quantitative bioassays, in order to determine the UV photoprotective capacity of the cell, for preventing inactivation of the insecticidal activity of the protein. The non-encapsulated and purified protein was exposed to the UV light showing a LC50 of 518 ng/cm2 against Spodoptera littoralis larvae, whereas the exposed encapsulated protein exhibited 479 ng/cm2. In addition to the capability to accumulate Vip3 proteins for the development of novel insecticidal formulates, the B. megaterium cell has demonstrated to provide moderate protection against the deleterious action of UV light.