Combining pharmacokinetic and electrophysiological models for early prediction of drug-induced arrhythmogenicity

This repository contains the code used to generate the male and female population of models and simulate the different pharmacokinetic scenarios in Llopis-Lorente et al. (2023). Combining pharmacokinetic and electrophysiological models for early prediction of drug-induced arrhythmogenicity

Detalles Bibliográficos
Autores: Llopis-Lorente, Jordi, Baroudi, Samuel, Koloskoff, Kévin, Basset, Matthieu, Benito, Sylvain, Dayan, Frederic, Romero Pérez, Lucia|||0000-0003-4605-8630, Mora-Fenoll, María Teresa|||0000-0002-8069-2486, Saiz Rodríguez, Francisco Javier|||0000-0002-9850-0825, Trenor Gomis, Beatriz Ana|||0000-0001-9166-6112
Tipo de recurso: conjunto de datos
Fecha de publicación:2023
País:España
Institución:Universitat Politècnica de València (UPV)
Repositorio:RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
Idioma:inglés
OAI Identifier:oai:riunet.upv.es:10251/193255
Acceso en línea:https://riunet.upv.es/handle/10251/193255
Access Level:acceso abierto
Palabra clave:Pharmacokinetic modeling
Torsade de Pointes
Cardiac safety
Population of models
Sex-specific cardiotoxicity
Descripción
Sumario:This repository contains the code used to generate the male and female population of models and simulate the different pharmacokinetic scenarios in Llopis-Lorente et al. (2023). Combining pharmacokinetic and electrophysiological models for early prediction of drug-induced arrhythmogenicity

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