Encapsulation techniques to enhance astaxanthin utilization as functional feed ingredient

This article belongs to the Special Issue Marine Carotenoids: Properties, Health Benefits, and Applications.

Detalles Bibliográficos
Autores: Vitale, Matteo, Gómez Estaca, Joaquín, Chung, Janete, Chua, Seong-Chea, Pampanin, Daniela Maria
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2025
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/385749
Acceso en línea:http://hdl.handle.net/10261/385749
Access Level:acceso abierto
Palabra clave:Astaxanthin
Aquaculture
Encapsulation
In vitro testing
Fish cell lines
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spelling Encapsulation techniques to enhance astaxanthin utilization as functional feed ingredientVitale, MatteoGómez Estaca, JoaquínChung, JaneteChua, Seong-CheaPampanin, Daniela MariaAstaxanthinAquacultureEncapsulationIn vitro testingFish cell linesThis article belongs to the Special Issue Marine Carotenoids: Properties, Health Benefits, and Applications.Herein, the effectiveness of astaxanthin (AX) as functional feed ingredient was assessed by enhancing its stability and bioavailability using encapsulation methods. Spray-drying and liposome entrapment were applied to a natural AX source from shrimp by-products, along with two commercially synthetic alternatives. Encapsulated AX formulations were evaluated for their physico-chemical properties, thermal stability, and in vitro performance using RTL-W1, a rainbow trout (Oncorhynchus mykiss) liver-derived cell line. Both techniques achieved high encapsulation efficiency (73–89%) and provided remarkable protection to AX during thermal treatments, maintaining its stability at 80 °C for up to 2 h and at 100 °C for 30 min. Nevertheless, neither encapsulation methods significantly mitigated water absorption over time. Additionally, morphological characterization revealed spray-dried microcapsules with typical round, partially collapsed particles with a broad size distribution, while liposomes further stabilized into dry powders by spray-drying showed structural rearrangements and an increase in size upon rehydration, although maintaining a uniform and stable distribution. In vitro testing revealed enhanced RTL-W1 cell viability and reduced reactive oxygen species (ROS) production when encapsulation was employed. Overall, these findings demonstrate the potential of the selected encapsulation techniques to optimize the stability, bioavailability, and functionality of AX, providing valuable insights to improve its utilization as a functional ingredient in fish feed formulations.This research was funded by the Research Council of Norway (NFR) under grant #336672, In vitro methods for screening novel ingredients, under the Innovation Project Industrial Sector Ph.D. program.Peer reviewedMultidisciplinary Digital Publishing InstituteResearch Council of NorwayVitale, Matteo [0000-0002-5954-0947]Gómez Estaca, Joaquín [0000-0003-1324-5739]Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]2025202520252025info:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_6501Publisher's versioninfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://hdl.handle.net/10261/385749reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)InglésVitale, Matteo; Gómez Estaca, Joaquín; Chung, Janete; Chua, Seong-Chea; Pampanin, Daniela Maria; 2025; Supplementary Materials: Encapsulation techniques to enhance astaxanthin utilization as functional feed ingredient [Dataset]; Multidisciplinary Digital Publishing Institute; https://doi.org/10.3390/md23040143https://doi.org/10.3390/md23040143Síinfo:eu-repo/semantics/openAccessoai:digital.csic.es:10261/3857492026-05-22T06:33:51Z
dc.title.none.fl_str_mv Encapsulation techniques to enhance astaxanthin utilization as functional feed ingredient
title Encapsulation techniques to enhance astaxanthin utilization as functional feed ingredient
spellingShingle Encapsulation techniques to enhance astaxanthin utilization as functional feed ingredient
Vitale, Matteo
Astaxanthin
Aquaculture
Encapsulation
In vitro testing
Fish cell lines
title_short Encapsulation techniques to enhance astaxanthin utilization as functional feed ingredient
title_full Encapsulation techniques to enhance astaxanthin utilization as functional feed ingredient
title_fullStr Encapsulation techniques to enhance astaxanthin utilization as functional feed ingredient
title_full_unstemmed Encapsulation techniques to enhance astaxanthin utilization as functional feed ingredient
title_sort Encapsulation techniques to enhance astaxanthin utilization as functional feed ingredient
dc.creator.none.fl_str_mv Vitale, Matteo
Gómez Estaca, Joaquín
Chung, Janete
Chua, Seong-Chea
Pampanin, Daniela Maria
author Vitale, Matteo
author_facet Vitale, Matteo
Gómez Estaca, Joaquín
Chung, Janete
Chua, Seong-Chea
Pampanin, Daniela Maria
author_role author
author2 Gómez Estaca, Joaquín
Chung, Janete
Chua, Seong-Chea
Pampanin, Daniela Maria
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Research Council of Norway
Vitale, Matteo [0000-0002-5954-0947]
Gómez Estaca, Joaquín [0000-0003-1324-5739]
Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]
dc.subject.none.fl_str_mv Astaxanthin
Aquaculture
Encapsulation
In vitro testing
Fish cell lines
topic Astaxanthin
Aquaculture
Encapsulation
In vitro testing
Fish cell lines
description This article belongs to the Special Issue Marine Carotenoids: Properties, Health Benefits, and Applications.
publishDate 2025
dc.date.none.fl_str_mv 2025
2025
2025
2025
dc.type.none.fl_str_mv info:eu-repo/semantics/article
http://purl.org/coar/resource_type/c_6501
Publisher's version
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10261/385749
url http://hdl.handle.net/10261/385749
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Vitale, Matteo; Gómez Estaca, Joaquín; Chung, Janete; Chua, Seong-Chea; Pampanin, Daniela Maria; 2025; Supplementary Materials: Encapsulation techniques to enhance astaxanthin utilization as functional feed ingredient [Dataset]; Multidisciplinary Digital Publishing Institute; https://doi.org/10.3390/md23040143
https://doi.org/10.3390/md23040143
Sí
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Multidisciplinary Digital Publishing Institute
publisher.none.fl_str_mv Multidisciplinary Digital Publishing Institute
dc.source.none.fl_str_mv reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC
instname:Consejo Superior de Investigaciones Científicas (CSIC)
instname_str Consejo Superior de Investigaciones Científicas (CSIC)
reponame_str DIGITAL.CSIC. Repositorio Institucional del CSIC
collection DIGITAL.CSIC. Repositorio Institucional del CSIC
repository.name.fl_str_mv
repository.mail.fl_str_mv
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