Estimation of parameters in a structured SIR model

[EN] In this paper, an age-structured epidemiological process is considered. The disease model is based on a SIR model with unknown parameters. We addressed two important issues to analyzing the model and its parameters. One issue is concerned with the theoretical existence of unique solution, the i...

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Detalles Bibliográficos
Autores: Cantó Colomina, Begoña|||0000-0002-9837-3926, Coll, Carmen|||0000-0002-6487-3922, Sánchez, Elena|||0000-0002-0972-6612
Tipo de recurso: artículo
Fecha de publicación:2017
País:España
Institución:Universitat Politècnica de València (UPV)
Repositorio:RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
Idioma:inglés
OAI Identifier:oai:riunet.upv.es:10251/102302
Acceso en línea:https://riunet.upv.es/handle/10251/102302
Access Level:acceso abierto
Palabra clave:Epidemic process
Mathematical modeling
Parameter estimation
Identifiability
Discrete-time system
MATEMATICA APLICADA
Descripción
Sumario:[EN] In this paper, an age-structured epidemiological process is considered. The disease model is based on a SIR model with unknown parameters. We addressed two important issues to analyzing the model and its parameters. One issue is concerned with the theoretical existence of unique solution, the identifiability problem. The second issue is how to estimate the parameters in the model. We propose an iterative algorithm to study the identifiability of the system and a method to estimate the parameters which are identifiable. A least squares approach based on a finite set of observations helps us to estimate the initial values of the parameters. Finally, we test the proposed algorithms.