Betaine increases net portal absorption of volatile fatty acids in Iberian pigs
[EN] Betaine is an osmolyte with the potential to increase volatile fatty acids (VFAs) production and hence improve intestinal health.The present study investigated how betaine affects portal and arterial concentrations and net portal absorption (NPA) of VFA in growing Iberian pigs. Eight 30 kg BW I...
| Autores: | , , , , , |
|---|---|
| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2021 |
| País: | España |
| Institución: | Universidad Rey Juan Carlos |
| Repositorio: | BULERIA. Repositorio Institucional de la Universidad de León |
| OAI Identifier: | oai:buleria.unileon.es:10612/18842 |
| Acceso en línea: | https://www.sciencedirect.com/science/article/pii/S1751731121000392?via%3Dihub https://hdl.handle.net/10612/18842 |
| Access Level: | acceso abierto |
| Palabra clave: | Sanidad animal Bacterial population Fermentation Net portal flux Short chain fatty acids Sus scrofa mediterraneus 3109 Ciencias Veterinarias |
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Betaine increases net portal absorption of volatile fatty acids in Iberian pigsLachica, M.Saro Higuera, CristinaMateos Álvarez, IvánGómez García, ManuelRanilla García, María JoséFernández Fígares, IgnacioSanidad animalBacterial populationFermentationNet portal fluxShort chain fatty acidsSus scrofa mediterraneus3109 Ciencias Veterinarias[EN] Betaine is an osmolyte with the potential to increase volatile fatty acids (VFAs) production and hence improve intestinal health.The present study investigated how betaine affects portal and arterial concentrations and net portal absorption (NPA) of VFA in growing Iberian pigs. Eight 30 kg BW Iberian growing barrows with indwelling catheters in portal vein, ileal vein and carotid artery were randomly assigned to a control diet or a diet supplemented with 0.5% betaine. Para-aminohippuric acid was infused into the ileal vein as a marker to determine portal blood flow using the dilution method. Blood samples were simultaneously taken from the carotid artery and portal vein at −60, 60, 120, 180, 240, 300 and 360 min after feeding 1 200 g of the diet. The NPA of VFA (acetate, propionate, butyrate, valerate, isobutyrate and caproate) was determined by multiplying the porto-arterial plasma concentration differences by portal plasma flow. Betaine increased NPA of acetate (1.44 fold; P < 0.001) and total VFA (0.55 fold; P < 0.001) while decreased NPA of propionate (−0.38 fold; P < 0.05) and valerate (−1.46 fold; P < 0.05) compared with control pigs. Estimated heat production potentially derived from NPA of VFA accounted for 0.20–0.27 of metabolizable energy for maintenance. Acetate and propionate accounted for most of the total VFA estimated heat production (0.83–0.89). Regarding bacterial communities, betaine apparently did not change the DNA abundance of fecal total bacteria, Lactobacillus, Bifidobacterium, Enterobacteriaceae, Bacteroides and the Clostridium clusters I, IV and XIV. In conclusion, betaine increased portal appearance and NPA of VFA, contributing to cover maintenance energy requirementsSIThis research was supported by grant AGL2016-80231-R from Ministerio de Economía, Industria y Competitividad, Spain. M. Gómez-García was supported by grant LE131-18 from Junta de Castilla y León co-financed by the European Social FundElsevierProducción AnimalFacultad de Veterinaria2021info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttps://www.sciencedirect.com/science/article/pii/S1751731121000392?via%3Dihubhttps://hdl.handle.net/10612/18842reponame:BULERIA. Repositorio Institucional de la Universidad de Leóninstname:Universidad Rey Juan CarlosIngléshttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessoai:buleria.unileon.es:10612/188422026-06-24T12:43:27Z |
| dc.title.none.fl_str_mv |
Betaine increases net portal absorption of volatile fatty acids in Iberian pigs |
| title |
Betaine increases net portal absorption of volatile fatty acids in Iberian pigs |
| spellingShingle |
Betaine increases net portal absorption of volatile fatty acids in Iberian pigs Lachica, M. Sanidad animal Bacterial population Fermentation Net portal flux Short chain fatty acids Sus scrofa mediterraneus 3109 Ciencias Veterinarias |
| title_short |
Betaine increases net portal absorption of volatile fatty acids in Iberian pigs |
| title_full |
Betaine increases net portal absorption of volatile fatty acids in Iberian pigs |
| title_fullStr |
Betaine increases net portal absorption of volatile fatty acids in Iberian pigs |
| title_full_unstemmed |
Betaine increases net portal absorption of volatile fatty acids in Iberian pigs |
| title_sort |
Betaine increases net portal absorption of volatile fatty acids in Iberian pigs |
| dc.creator.none.fl_str_mv |
Lachica, M. Saro Higuera, Cristina Mateos Álvarez, Iván Gómez García, Manuel Ranilla García, María José Fernández Fígares, Ignacio |
| author |
Lachica, M. |
| author_facet |
Lachica, M. Saro Higuera, Cristina Mateos Álvarez, Iván Gómez García, Manuel Ranilla García, María José Fernández Fígares, Ignacio |
| author_role |
author |
| author2 |
Saro Higuera, Cristina Mateos Álvarez, Iván Gómez García, Manuel Ranilla García, María José Fernández Fígares, Ignacio |
| author2_role |
author author author author author |
| dc.contributor.none.fl_str_mv |
Producción Animal Facultad de Veterinaria |
| dc.subject.none.fl_str_mv |
Sanidad animal Bacterial population Fermentation Net portal flux Short chain fatty acids Sus scrofa mediterraneus 3109 Ciencias Veterinarias |
| topic |
Sanidad animal Bacterial population Fermentation Net portal flux Short chain fatty acids Sus scrofa mediterraneus 3109 Ciencias Veterinarias |
| description |
[EN] Betaine is an osmolyte with the potential to increase volatile fatty acids (VFAs) production and hence improve intestinal health.The present study investigated how betaine affects portal and arterial concentrations and net portal absorption (NPA) of VFA in growing Iberian pigs. Eight 30 kg BW Iberian growing barrows with indwelling catheters in portal vein, ileal vein and carotid artery were randomly assigned to a control diet or a diet supplemented with 0.5% betaine. Para-aminohippuric acid was infused into the ileal vein as a marker to determine portal blood flow using the dilution method. Blood samples were simultaneously taken from the carotid artery and portal vein at −60, 60, 120, 180, 240, 300 and 360 min after feeding 1 200 g of the diet. The NPA of VFA (acetate, propionate, butyrate, valerate, isobutyrate and caproate) was determined by multiplying the porto-arterial plasma concentration differences by portal plasma flow. Betaine increased NPA of acetate (1.44 fold; P < 0.001) and total VFA (0.55 fold; P < 0.001) while decreased NPA of propionate (−0.38 fold; P < 0.05) and valerate (−1.46 fold; P < 0.05) compared with control pigs. Estimated heat production potentially derived from NPA of VFA accounted for 0.20–0.27 of metabolizable energy for maintenance. Acetate and propionate accounted for most of the total VFA estimated heat production (0.83–0.89). Regarding bacterial communities, betaine apparently did not change the DNA abundance of fecal total bacteria, Lactobacillus, Bifidobacterium, Enterobacteriaceae, Bacteroides and the Clostridium clusters I, IV and XIV. In conclusion, betaine increased portal appearance and NPA of VFA, contributing to cover maintenance energy requirements |
| publishDate |
2021 |
| dc.date.none.fl_str_mv |
2021 |
| dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.none.fl_str_mv |
https://www.sciencedirect.com/science/article/pii/S1751731121000392?via%3Dihub https://hdl.handle.net/10612/18842 |
| url |
https://www.sciencedirect.com/science/article/pii/S1751731121000392?via%3Dihub https://hdl.handle.net/10612/18842 |
| dc.language.none.fl_str_mv |
Inglés |
| language_invalid_str_mv |
Inglés |
| dc.rights.none.fl_str_mv |
http://creativecommons.org/licenses/by-nc-nd/4.0/ info:eu-repo/semantics/openAccess |
| rights_invalid_str_mv |
http://creativecommons.org/licenses/by-nc-nd/4.0/ |
| eu_rights_str_mv |
openAccess |
| dc.publisher.none.fl_str_mv |
Elsevier |
| publisher.none.fl_str_mv |
Elsevier |
| dc.source.none.fl_str_mv |
reponame:BULERIA. Repositorio Institucional de la Universidad de León instname:Universidad Rey Juan Carlos |
| instname_str |
Universidad Rey Juan Carlos |
| reponame_str |
BULERIA. Repositorio Institucional de la Universidad de León |
| collection |
BULERIA. Repositorio Institucional de la Universidad de León |
| repository.name.fl_str_mv |
|
| repository.mail.fl_str_mv |
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1869415613295755264 |
| score |
15,301603 |