Deep Sequencing Reveals Occult Mansonellosis Coinfections in Residents From the Brazilian Amazon Village of São Gabriel da Cachoeira

Mansonella ozzardi and Mansonella perstans infections both cause mansonellosis but are usually treated differently. Using a real-time polymerase chain reaction assay and deep sequencing, we reveal the presence of mansonellosis coinfections that were undetectable by standard diagnostic methods. Our r...

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Detalhes bibliográficos
Autores: Crainey, James Lee, Aguiar Costa, Carlos Henrique, Ferreira de Oliveira Leles, Lorena, Ribeiro da Silva, Túllio Romão, de Aquino Narzetti, Luiz Henrique, Vinícius Serra Dos Santos, Yago, Costa Conteville, Liliane, Costa Pessoa, Felipe Arley, Carvajal Cortés, José Joaquin, Paulo Vicente, Ana Carolina, Rubio Muñoz, Jose Miguel, Bessa Luz, Sérgio Luiz
Formato: artículo
Fecha de publicación:2020
País:España
Recursos:Instituto de Salud Carlos III (ISCIII)
Repositorio:Repisalud
Idioma:inglés
OAI Identifier:oai:repisalud.isciii.es:20.500.12105/26157
Acesso em linha:https://hdl.handle.net/20.500.12105/26157
Access Level:acceso abierto
Palavra-chave:Mansonella ozzardi
Mansonella perstans
Brazil
Coinfections
Mansonellosis
Animals
Coinfection
High-Throughput Nucleotide Sequencing
Humans
Mansonella
Mansonelliasis
Descrição
Resumo:Mansonella ozzardi and Mansonella perstans infections both cause mansonellosis but are usually treated differently. Using a real-time polymerase chain reaction assay and deep sequencing, we reveal the presence of mansonellosis coinfections that were undetectable by standard diagnostic methods. Our results confirm mansonellosis coinfections and have important implications for the disease's treatment and diagnosis.

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