B-cell leukemia transdifferentiation to macrophage involves reconfiguration of DNA methylation for long-range regulation

This work was supported by the Health Department PERIS-project no. SLT/002/16/00374 and AGAUR-projects no. 2017SGR1080, 2014SGR633, 2017SGR1033, and 2009SGR1315 of the Catalan Government (Generalitat de Catalunya); the Spanish Institute of Health Carlos III (ISCIII) project no. DTS16/00153, and CIBE...

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Authors: Bueno-Costa, Alberto, Piñeyro, David, Soler, Marta, Javierre, Biola M., Raurell Vila, Helena, Subirana-Granés, Marc, Pasquali, Lorenzo, Martinez-Climent, Jose A., Esteller, Manel
Format: article
Status:Published version
Publication Date:2020
Country:España
Institution:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repository:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:10230/52455
Online Access:http://hdl.handle.net/10230/52455
http://dx.doi.org/10.1038/s41375-019-0643-1
Access Level:Open access
Keyword:Acute lymphocytic leukaemia
Haematopoietic stem cells
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spelling B-cell leukemia transdifferentiation to macrophage involves reconfiguration of DNA methylation for long-range regulationBueno-Costa, AlbertoPiñeyro, DavidSoler, MartaJavierre, Biola M.Raurell Vila, HelenaSubirana-Granés, MarcPasquali, LorenzoMartinez-Climent, Jose A.Esteller, ManelAcute lymphocytic leukaemiaHaematopoietic stem cellsThis work was supported by the Health Department PERIS-project no. SLT/002/16/00374 and AGAUR-projects no. 2017SGR1080, 2014SGR633, 2017SGR1033, and 2009SGR1315 of the Catalan Government (Generalitat de Catalunya); the Spanish Institute of Health Carlos III (ISCIII) project no. DTS16/00153, and CIBERONC CB16/12/00312 and CB16/12/00489; and Ministerio de Economía y Competitividad (MINECO) project nos. SAF2014-55000-R, BFU2014-57466-P, SAF2017-89673-R, SAF2017-86242-R, and SAF2015-70270-REDT cofinanced by the European Development Regional Fund, ‘A way to achieve Europe’ ERDF; the Cellex Foundation; and “la Caixa” Bank Foundation (LCF/PR/GN18/51140001). We thank Dr Thomas Graf for providing the transdifferentiation model.Nature Research202220222020info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/pdfhttp://hdl.handle.net/10230/52455http://dx.doi.org/10.1038/s41375-019-0643-1reponame:Recercat. Dipósit de la Recerca de Catalunyainstname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)InglésLeukemia. 2020;34(4):1158-62info:eu-repo/grantAgreement/ES/1PE/SAF2014-55000-Rinfo:eu-repo/grantAgreement/ES/1PE/BFU2014-57466-Pinfo:eu-repo/grantAgreement/ES/2PE/SAF2017-89673-Rinfo:eu-repo/grantAgreement/ES/2PE/SAF2017-86242-Rinfo:eu-repo/grantAgreement/ES/1PE/SAF2015-70270-REDT© The Author(s) 2019. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.http://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:recercat.cat:10230/524552026-05-29T05:05:01Z
dc.title.none.fl_str_mv B-cell leukemia transdifferentiation to macrophage involves reconfiguration of DNA methylation for long-range regulation
title B-cell leukemia transdifferentiation to macrophage involves reconfiguration of DNA methylation for long-range regulation
spellingShingle B-cell leukemia transdifferentiation to macrophage involves reconfiguration of DNA methylation for long-range regulation
Bueno-Costa, Alberto
Acute lymphocytic leukaemia
Haematopoietic stem cells
title_short B-cell leukemia transdifferentiation to macrophage involves reconfiguration of DNA methylation for long-range regulation
title_full B-cell leukemia transdifferentiation to macrophage involves reconfiguration of DNA methylation for long-range regulation
title_fullStr B-cell leukemia transdifferentiation to macrophage involves reconfiguration of DNA methylation for long-range regulation
title_full_unstemmed B-cell leukemia transdifferentiation to macrophage involves reconfiguration of DNA methylation for long-range regulation
title_sort B-cell leukemia transdifferentiation to macrophage involves reconfiguration of DNA methylation for long-range regulation
dc.creator.none.fl_str_mv Bueno-Costa, Alberto
Piñeyro, David
Soler, Marta
Javierre, Biola M.
Raurell Vila, Helena
Subirana-Granés, Marc
Pasquali, Lorenzo
Martinez-Climent, Jose A.
Esteller, Manel
author Bueno-Costa, Alberto
author_facet Bueno-Costa, Alberto
Piñeyro, David
Soler, Marta
Javierre, Biola M.
Raurell Vila, Helena
Subirana-Granés, Marc
Pasquali, Lorenzo
Martinez-Climent, Jose A.
Esteller, Manel
author_role author
author2 Piñeyro, David
Soler, Marta
Javierre, Biola M.
Raurell Vila, Helena
Subirana-Granés, Marc
Pasquali, Lorenzo
Martinez-Climent, Jose A.
Esteller, Manel
author2_role author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Acute lymphocytic leukaemia
Haematopoietic stem cells
topic Acute lymphocytic leukaemia
Haematopoietic stem cells
description This work was supported by the Health Department PERIS-project no. SLT/002/16/00374 and AGAUR-projects no. 2017SGR1080, 2014SGR633, 2017SGR1033, and 2009SGR1315 of the Catalan Government (Generalitat de Catalunya); the Spanish Institute of Health Carlos III (ISCIII) project no. DTS16/00153, and CIBERONC CB16/12/00312 and CB16/12/00489; and Ministerio de Economía y Competitividad (MINECO) project nos. SAF2014-55000-R, BFU2014-57466-P, SAF2017-89673-R, SAF2017-86242-R, and SAF2015-70270-REDT cofinanced by the European Development Regional Fund, ‘A way to achieve Europe’ ERDF; the Cellex Foundation; and “la Caixa” Bank Foundation (LCF/PR/GN18/51140001). We thank Dr Thomas Graf for providing the transdifferentiation model.
publishDate 2020
dc.date.none.fl_str_mv 2020
2022
2022
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10230/52455
http://dx.doi.org/10.1038/s41375-019-0643-1
url http://hdl.handle.net/10230/52455
http://dx.doi.org/10.1038/s41375-019-0643-1
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Leukemia. 2020;34(4):1158-62
info:eu-repo/grantAgreement/ES/1PE/SAF2014-55000-R
info:eu-repo/grantAgreement/ES/1PE/BFU2014-57466-P
info:eu-repo/grantAgreement/ES/2PE/SAF2017-89673-R
info:eu-repo/grantAgreement/ES/2PE/SAF2017-86242-R
info:eu-repo/grantAgreement/ES/1PE/SAF2015-70270-REDT
dc.rights.none.fl_str_mv http://creativecommons.org/licenses/by/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Nature Research
publisher.none.fl_str_mv Nature Research
dc.source.none.fl_str_mv reponame:Recercat. Dipósit de la Recerca de Catalunya
instname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
instname_str Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
reponame_str Recercat. Dipósit de la Recerca de Catalunya
collection Recercat. Dipósit de la Recerca de Catalunya
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,812429

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