B-cell leukemia transdifferentiation to macrophage involves reconfiguration of DNA methylation for long-range regulation

This work was supported by the Health Department PERIS-project no. SLT/002/16/00374 and AGAUR-projects no. 2017SGR1080, 2014SGR633, 2017SGR1033, and 2009SGR1315 of the Catalan Government (Generalitat de Catalunya); the Spanish Institute of Health Carlos III (ISCIII) project no. DTS16/00153, and CIBE...

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Detalles Bibliográficos
Autores: Bueno-Costa, Alberto, Piñeyro, David, Soler, Marta, Javierre, Biola M., Raurell Vila, Helena, Subirana-Granés, Marc, Pasquali, Lorenzo, Martinez-Climent, Jose A., Esteller, Manel
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2020
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:10230/52455
Acceso en línea:http://hdl.handle.net/10230/52455
http://dx.doi.org/10.1038/s41375-019-0643-1
Access Level:acceso abierto
Palabra clave:Acute lymphocytic leukaemia
Haematopoietic stem cells
Descripción
Sumario:This work was supported by the Health Department PERIS-project no. SLT/002/16/00374 and AGAUR-projects no. 2017SGR1080, 2014SGR633, 2017SGR1033, and 2009SGR1315 of the Catalan Government (Generalitat de Catalunya); the Spanish Institute of Health Carlos III (ISCIII) project no. DTS16/00153, and CIBERONC CB16/12/00312 and CB16/12/00489; and Ministerio de Economía y Competitividad (MINECO) project nos. SAF2014-55000-R, BFU2014-57466-P, SAF2017-89673-R, SAF2017-86242-R, and SAF2015-70270-REDT cofinanced by the European Development Regional Fund, ‘A way to achieve Europe’ ERDF; the Cellex Foundation; and “la Caixa” Bank Foundation (LCF/PR/GN18/51140001). We thank Dr Thomas Graf for providing the transdifferentiation model.

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