Associations between Both Lignan and Yogurt Consumption and Cardiovascular Risk Parameters in an Elderly Population: Observations from a Cross-Sectional Approach in the PREDIMED Study
Background The study of dietary patterns is gaining interest. Although the health benefits of yogurt and lignans have been investigated separately, to our knowledge there are no studies on their associative effects. Objective The aim of this study was to evaluate a possible association between yogur...
| Autores: | , , , , , , , , , , , , , , , , , , , , |
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| Tipo de recurso: | artículo |
| Fecha de publicación: | 2017 |
| País: | España |
| Institución: | Instituto de Salud Carlos III (ISCIII) |
| Repositorio: | Repisalud |
| Idioma: | inglés |
| OAI Identifier: | oai:repisalud.isciii.es:20.500.12105/20486 |
| Acceso en línea: | http://hdl.handle.net/20.500.12105/20486 |
| Access Level: | acceso abierto |
| Palabra clave: | Polyphenol Lipid profile Cardiovascular disease Microbiota Índice de Masa Corporal Modelos Lineales Dieta Mediterránea Yogur LDL-Colesterol Femenino Lignanos HDL-Colesterol Masculino Circunferencia de la Cintura Estudios Transversales Factores de Riesgo Presión Sanguínea Humanos Persona de Mediana Edad Glucemia Ingestión de Energía Anciano Encuestas y Cuestionarios Enfermedades Cardiovasculares Triglicéridos Ensayos Clínicos Controlados Aleatorios como Asunto España Cardiovascular Diseases Triglycerides Aged Randomized Controlled Trials as Topic Blood Glucose Energy Intake Spain Humans Middle Aged Blood Pressure Cross-Sectional Studies Male Cholesterol, LDL Cholesterol, HDL Female Lignans Risk Factors Yogurt Body Mass Index Diet, Mediterranean Linear Models |
| Sumario: | Background The study of dietary patterns is gaining interest. Although the health benefits of yogurt and lignans have been investigated separately, to our knowledge there are no studies on their associative effects. Objective The aim of this study was to evaluate a possible association between yogurt and lignans using biomarkers of cardiovascular disease risk in an elderly population. Design We conducted a cross-sectional analysis of the association between baseline dietary information and cardiovascular risk parameters using food frequency questionnaires. Participants We enrolled 7,169 Spanish participants of the PREDIMED (Prevencion con Dieta Mediterranea) study (elderly men and women at high cardiovascular risk) from June 2003 to June 2009. Main outcome measures Cardiovascular risk parameters, including cholesterol, tri-glycerides, glucose, body mass index, weight, waist circumference, and blood pressure were measured. Statistical analysis General linear models were used to assess the relationship between categorical variables (yogurt, total dairy intake, lignans, and yogurt plus lignans) and cardiovascular risk parameters. Results The consumption of either yogurt or lignans seems to have beneficial effects on human health, but the consumption of both showed greater improvement in some cardiovascular health parameters. Indeed, participants with a higher consumption of both yogurt and lignans showed lower total cholesterol (estimated beta-coefficients= -6.18; P=0.001) and low-density lipoprotein cholesterol levels (beta=-4.92; P=0.005). In contrast, participants with lower yogurt and lignan consumption had a higher body mass index (beta=0.28; P=0.007) and weight (beta=1.20; P=0.008). Conclusions High lignan and yogurt consumption is associated with a better cardiovascular risk parameters profile in an elderly Mediterranean population. Further research is warranted to determine the mechanisms and consequences of this potential effect. |
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