Highly Regio-Selective Organocatalytic formation of Carbamates from Substituted Cyclic Carbonates

A highly regio-selective catalytic approach has been developed towards carbamates derived from cyclic organic carbonates by reaction of the latter with amine reagents under organo-catalytic control. For various combinations of carbonate and amine substrates, an organocatalyst (TBD: triazabicyclodece...

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Detalles Bibliográficos
Autores: Sopeña, Sergio, Laserna, Victor, Guo, Wusheng, Martin, Eddy, Escudero-Adán, Eduardo C., Kleij, Arjan W.
Tipo de recurso: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2016
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2072/356054
Acceso en línea:http://hdl.handle.net/2072/356054
https://doi.org/10.1002/adsc.201600290
Access Level:acceso abierto
Palabra clave:54
Descripción
Sumario:A highly regio-selective catalytic approach has been developed towards carbamates derived from cyclic organic carbonates by reaction of the latter with amine reagents under organo-catalytic control. For various combinations of carbonate and amine substrates, an organocatalyst (TBD: triazabicyclodecene) was used to increase the reaction kinetics while exerting excellent regio- selective control. The current method is the first general approach towards the control over the regio-selectivity of this reaction using a wide variety of easily accessed substituted organic carbonates.