Chapter 10: Liquid–Liquid Colloidal Systems as Advanced Biomedical Nanocarriers

Liquid–liquid mixtures that include micro-, nano-, and water-in-water emulsions are versatile soft colloids widely used in pharmaceutical and biotechnological fields. These systems exhibit unique properties arising from their nanostructured nature (micro- and nanoemulsions) and confined domains (com...

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Detalles Bibliográficos
Autores: Peula-García, J. M., Vicario de la Torre, M., Esquena, Jordi
Tipo de recurso: otro
Estado:Versión aceptada para publicación
Fecha de publicación:2025
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:dnet:digitalcsic_::73059c1dbc485f04b8323e5e1731cb9c
Acceso en línea:http://hdl.handle.net/10261/425965
Access Level:acceso embargado
Palabra clave:Liquid–liquid mixtures
Colloids
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Descripción
Sumario:Liquid–liquid mixtures that include micro-, nano-, and water-in-water emulsions are versatile soft colloids widely used in pharmaceutical and biotechnological fields. These systems exhibit unique properties arising from their nanostructured nature (micro- and nanoemulsions) and confined domains (common to all three systems). Microemulsions are thermodynamically stable systems typically containing water, oil, surfactant, and often a co-surfactant, while nanoemulsions are kinetically biphasic systems that require energy input for nanodroplet formation. Water-in-water emulsions consist of two immiscible aqueous phases stabilized by particles or hydrophilic polymers. Because of their fully aqueous nature, these emulsions remain quite transparent. Understanding the phase behaviour and interfacial properties, stabilization, and formulation parameters is crucial for designing and tailoring the properties of microemulsions, nanoemulsions, and water-in-water emulsions for specific biomedical applications.