Substrate stiffness and pressure alter retinal Müller glia response and extracellular matrix production
[Background] The retina is highly influenced by its mechanical environment, with Müller glia (MG) acting as key mechanosensors and extracellular matrix (ECM) producers. This study examined MG responses to substrate stiffness and high pressure (HP), and whether TGF-β1 modulation could mitigate these...
| Autores: | , , , , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2025 |
| País: | España |
| Institución: | Consejo Superior de Investigaciones Científicas (CSIC) |
| Repositorio: | DIGITAL.CSIC. Repositorio Institucional del CSIC |
| OAI Identifier: | oai:digital.csic.es:10261/399111 |
| Acceso en línea: | http://hdl.handle.net/10261/399111 https://api.elsevier.com/content/abstract/scopus_id/105010072979 |
| Access Level: | acceso abierto |
| Palabra clave: | Extracellular matrix Müller glia Polyacrylamide gels Pressure Stiffness TGF-β1 |
| Sumario: | [Background] The retina is highly influenced by its mechanical environment, with Müller glia (MG) acting as key mechanosensors and extracellular matrix (ECM) producers. This study examined MG responses to substrate stiffness and high pressure (HP), and whether TGF-β1 modulation could mitigate these effects. |
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