Incidence, Clinical Characteristics and Management of Inflammatory Bowel Disease in Spain
(1) Aims: To assess the incidence of inflammatory bowel disease (IBD) in Spain, to describe the main epidemiological and clinical characteristics at diagnosis and the evolution of the disease, and to explore the use of drug treatments. (2) Methods: Prospective, population-based nationwide registry....
| Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Format: | article |
| Publication Date: | 2021 |
| Country: | España |
| Institution: | Universitat Autònoma de Barcelona |
| Repository: | Dipòsit Digital de Documents de la UAB |
| Language: | English |
| OAI Identifier: | oai:ddd.uab.cat:256468 |
| Online Access: | https://ddd.uab.cat/record/256468 https://dx.doi.org/urn:doi:10.3390/jcm10132885 |
| Access Level: | Open access |
| Keyword: | Epidemiology Incidence Inflammatory bowel disease Crohn's disease Ulcerative colitis |
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oai:ddd.uab.cat:256468 |
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España |
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| dc.title.none.fl_str_mv |
Incidence, Clinical Characteristics and Management of Inflammatory Bowel Disease in Spain Large-Scale Epidemiological Study |
| title |
Incidence, Clinical Characteristics and Management of Inflammatory Bowel Disease in Spain |
| spellingShingle |
Incidence, Clinical Characteristics and Management of Inflammatory Bowel Disease in Spain Chaparro, María|||0000-0002-9275-4242 Epidemiology Incidence Inflammatory bowel disease Crohn's disease Ulcerative colitis |
| title_short |
Incidence, Clinical Characteristics and Management of Inflammatory Bowel Disease in Spain |
| title_full |
Incidence, Clinical Characteristics and Management of Inflammatory Bowel Disease in Spain |
| title_fullStr |
Incidence, Clinical Characteristics and Management of Inflammatory Bowel Disease in Spain |
| title_full_unstemmed |
Incidence, Clinical Characteristics and Management of Inflammatory Bowel Disease in Spain |
| title_sort |
Incidence, Clinical Characteristics and Management of Inflammatory Bowel Disease in Spain |
| dc.creator.none.fl_str_mv |
Chaparro, María|||0000-0002-9275-4242 Garre, Ana Núñez Ortiz, Andrea Diz-Lois Palomares, María Teresa Rodríguez Gutiérrez, Cristina|||0000-0003-3954-0736 Riestra, Sabino|||0000-0002-9383-3698 Vela, Milagros|||0000-0003-4537-9133 Benítez, José Manuel|||0000-0001-8898-3141 Fernández Salgado, Estela Sánchez Rodríguez, Eugenia Hernández, Vicent|||0000-0003-1607-0831 Ferreiro Iglesias, Rocío|||0000-0002-0469-4332 Ponferrada Díaz, Ángel|||0000-0002-1176-276X Barrio, Jesús|||0000-0001-7087-3921 Huguet, José María|||0000-0001-6486-1262 Sicilia Aladrén, Beatriz|||0000-0002-4495-9358 Martín-Arranz, María Dolores|||0000-0002-1872-0917 Calvet, Xavier|||0000-0002-6278-9663 Ginard, Daniel Alonso-Abreu, Inmaculada|||0000-0003-0406-029X Fernández-Salazar, Luis|||0000-0002-9951-7979 Varela Trastoy, Pilar Rivero, Montserrat|||0000-0002-5834-1559 Vera-Mendoza, Isabel Vega Villaamil, Pablo|||0000-0001-7545-6297 Navarro, Pablo|||0000-0001-6228-3462 Sierra Ausín, Mónica|||0000-0003-3342-8209 Cabriada, José Luis|||0000-0002-3068-5659 Aguas, Mariam|||0000-0003-4353-569X Vicente, Raquel|||0000-0002-7605-3534 Navarro-Llavat, Mercè|||0000-0002-1132-0427 Echarri, Ana|||0000-0001-6690-7543 Gomollón, Fernando|||0000-0003-0076-3529 Guerra del Río, Elena Piñero, Concepción Casanova, María José|||0000-0001-8233-9638 Spicakova, Katerina Ortiz de Zarate, Jone Torrella Cortés, Emilio Gutiérrez Casbas, Ana|||0000-0002-5460-4139 Alonso-Galán, Horacio Hernández-Martínez, Álvaro Marrero, José Miguel|||0000-0001-9445-3921 Lorente Poyatos, Rufo|||0000-0003-0709-2932 Calafat, Margalida|||0000-0003-2335-3792 Martí Romero, Lidia Robledo, Pilar Bosch, Orencio Jiménez, Nuria Esteve, Maria|||0000-0001-7716-0027 Duque, José María Fuentes Coronel, Ana María|||0000-0001-8862-0922 Josefa Sampedro, Manuela Sesé Abizanda, Eva Herreros Martínez, Belén Pozzati, Liliana Fernández Rosáenz, Hipólito Crespo Suarez, Belén López Serrano, Pilar|||0000-0003-4488-5376 Lucendo, Alfredo J.|||0000-0003-1183-1072 Muñoz Vicente, Margarita Bermejo, Fernando|||0000-0003-4610-0886 Ramírez Palanca, José Joaquín Menacho, Margarita Carmona, Amalia Camargo, Raquel Torra Alsina, Sandra Maroto, Nuria Nerín de la Puerta, Juan Castro Ortiz, Elena Marín Jiménez, Ignacio|||0000-0001-5424-2484 Botella, Belén Sapiña, Amparo Cruz, Noelia Forcelledo, José Luis F. Bouhmidi, Abdel Castaño-Milla, Carlos Opio, Verónica Nicolás, Isabel Kutz, Marcos Abraldes Bechiarelli, Alfredo Gordillo, Jordi|||0000-0001-6418-0715 Ber, Yolanda|||0000-0002-5184-8349 Torres Domínguez, Yolanda Novella Durán, María Teresa Rodríguez Mondéjar, Silvia Martínez-Cerezo, Francisco J. Kolle, Lilyan Ledezma, Cesar Iyo, Eduardo Roncero, Oscar Irisarri, Rebeca Lluis, Laia Blázquez Gómez, Isabel Zapata, Eva María José Alcalá, María Martínez Pascual, Cristina Montealegre, María Mata, Laura Monrobel, Ana Hernández Camba, Alejandro|||0000-0002-8653-207X Hernández Villalba, Luis|||0000-0002-9175-4312 Tejada, María Mir, Alberto Galve, María Luisa Soler Rodríguez, Marta Hervías, Daniel Gómez-Valero, José Antonio Barreiro de-Acosta, Manuel|||0000-0001-5915-1477 Rodríguez-Artalejo, Fernando|||0000-0001-9317-5755 García-Esquinas, Esther|||0000-0002-8688-5174 P. Gisbert, Javier|||0000-0003-2090-3445 |
| author |
Chaparro, María|||0000-0002-9275-4242 |
| author_facet |
Chaparro, María|||0000-0002-9275-4242 Garre, Ana Núñez Ortiz, Andrea Diz-Lois Palomares, María Teresa Rodríguez Gutiérrez, Cristina|||0000-0003-3954-0736 Riestra, Sabino|||0000-0002-9383-3698 Vela, Milagros|||0000-0003-4537-9133 Benítez, José Manuel|||0000-0001-8898-3141 Fernández Salgado, Estela Sánchez Rodríguez, Eugenia Hernández, Vicent|||0000-0003-1607-0831 Ferreiro Iglesias, Rocío|||0000-0002-0469-4332 Ponferrada Díaz, Ángel|||0000-0002-1176-276X Barrio, Jesús|||0000-0001-7087-3921 Huguet, José María|||0000-0001-6486-1262 Sicilia Aladrén, Beatriz|||0000-0002-4495-9358 Martín-Arranz, María Dolores|||0000-0002-1872-0917 Calvet, Xavier|||0000-0002-6278-9663 Ginard, Daniel Alonso-Abreu, Inmaculada|||0000-0003-0406-029X Fernández-Salazar, Luis|||0000-0002-9951-7979 Varela Trastoy, Pilar Rivero, Montserrat|||0000-0002-5834-1559 Vera-Mendoza, Isabel Vega Villaamil, Pablo|||0000-0001-7545-6297 Navarro, Pablo|||0000-0001-6228-3462 Sierra Ausín, Mónica|||0000-0003-3342-8209 Cabriada, José Luis|||0000-0002-3068-5659 Aguas, Mariam|||0000-0003-4353-569X Vicente, Raquel|||0000-0002-7605-3534 Navarro-Llavat, Mercè|||0000-0002-1132-0427 Echarri, Ana|||0000-0001-6690-7543 Gomollón, Fernando|||0000-0003-0076-3529 Guerra del Río, Elena Piñero, Concepción Casanova, María José|||0000-0001-8233-9638 Spicakova, Katerina Ortiz de Zarate, Jone Torrella Cortés, Emilio Gutiérrez Casbas, Ana|||0000-0002-5460-4139 Alonso-Galán, Horacio Hernández-Martínez, Álvaro Marrero, José Miguel|||0000-0001-9445-3921 Lorente Poyatos, Rufo|||0000-0003-0709-2932 Calafat, Margalida|||0000-0003-2335-3792 Martí Romero, Lidia Robledo, Pilar Bosch, Orencio Jiménez, Nuria Esteve, Maria|||0000-0001-7716-0027 Duque, José María Fuentes Coronel, Ana María|||0000-0001-8862-0922 Josefa Sampedro, Manuela Sesé Abizanda, Eva Herreros Martínez, Belén Pozzati, Liliana Fernández Rosáenz, Hipólito Crespo Suarez, Belén López Serrano, Pilar|||0000-0003-4488-5376 Lucendo, Alfredo J.|||0000-0003-1183-1072 Muñoz Vicente, Margarita Bermejo, Fernando|||0000-0003-4610-0886 Ramírez Palanca, José Joaquín Menacho, Margarita Carmona, Amalia Camargo, Raquel Torra Alsina, Sandra Maroto, Nuria Nerín de la Puerta, Juan Castro Ortiz, Elena Marín Jiménez, Ignacio|||0000-0001-5424-2484 Botella, Belén Sapiña, Amparo Cruz, Noelia Forcelledo, José Luis F. Bouhmidi, Abdel Castaño-Milla, Carlos Opio, Verónica Nicolás, Isabel Kutz, Marcos Abraldes Bechiarelli, Alfredo Gordillo, Jordi|||0000-0001-6418-0715 Ber, Yolanda|||0000-0002-5184-8349 Torres Domínguez, Yolanda Novella Durán, María Teresa Rodríguez Mondéjar, Silvia Martínez-Cerezo, Francisco J. Kolle, Lilyan Ledezma, Cesar Iyo, Eduardo Roncero, Oscar Irisarri, Rebeca Lluis, Laia Blázquez Gómez, Isabel Zapata, Eva María José Alcalá, María Martínez Pascual, Cristina Montealegre, María Mata, Laura Monrobel, Ana Hernández Camba, Alejandro|||0000-0002-8653-207X Hernández Villalba, Luis|||0000-0002-9175-4312 Tejada, María Mir, Alberto Galve, María Luisa Soler Rodríguez, Marta Hervías, Daniel Gómez-Valero, José Antonio Barreiro de-Acosta, Manuel|||0000-0001-5915-1477 Rodríguez-Artalejo, Fernando|||0000-0001-9317-5755 García-Esquinas, Esther|||0000-0002-8688-5174 P. Gisbert, Javier|||0000-0003-2090-3445 |
| author_role |
author |
| author2 |
Garre, Ana Núñez Ortiz, Andrea Diz-Lois Palomares, María Teresa Rodríguez Gutiérrez, Cristina|||0000-0003-3954-0736 Riestra, Sabino|||0000-0002-9383-3698 Vela, Milagros|||0000-0003-4537-9133 Benítez, José Manuel|||0000-0001-8898-3141 Fernández Salgado, Estela Sánchez Rodríguez, Eugenia Hernández, Vicent|||0000-0003-1607-0831 Ferreiro Iglesias, Rocío|||0000-0002-0469-4332 Ponferrada Díaz, Ángel|||0000-0002-1176-276X Barrio, Jesús|||0000-0001-7087-3921 Huguet, José María|||0000-0001-6486-1262 Sicilia Aladrén, Beatriz|||0000-0002-4495-9358 Martín-Arranz, María Dolores|||0000-0002-1872-0917 Calvet, Xavier|||0000-0002-6278-9663 Ginard, Daniel Alonso-Abreu, Inmaculada|||0000-0003-0406-029X Fernández-Salazar, Luis|||0000-0002-9951-7979 Varela Trastoy, Pilar Rivero, Montserrat|||0000-0002-5834-1559 Vera-Mendoza, Isabel Vega Villaamil, Pablo|||0000-0001-7545-6297 Navarro, Pablo|||0000-0001-6228-3462 Sierra Ausín, Mónica|||0000-0003-3342-8209 Cabriada, José Luis|||0000-0002-3068-5659 Aguas, Mariam|||0000-0003-4353-569X Vicente, Raquel|||0000-0002-7605-3534 Navarro-Llavat, Mercè|||0000-0002-1132-0427 Echarri, Ana|||0000-0001-6690-7543 Gomollón, Fernando|||0000-0003-0076-3529 Guerra del Río, Elena Piñero, Concepción Casanova, María José|||0000-0001-8233-9638 Spicakova, Katerina Ortiz de Zarate, Jone Torrella Cortés, Emilio Gutiérrez Casbas, Ana|||0000-0002-5460-4139 Alonso-Galán, Horacio Hernández-Martínez, Álvaro Marrero, José Miguel|||0000-0001-9445-3921 Lorente Poyatos, Rufo|||0000-0003-0709-2932 Calafat, Margalida|||0000-0003-2335-3792 Martí Romero, Lidia Robledo, Pilar Bosch, Orencio Jiménez, Nuria Esteve, Maria|||0000-0001-7716-0027 Duque, José María Fuentes Coronel, Ana María|||0000-0001-8862-0922 Josefa Sampedro, Manuela Sesé Abizanda, Eva Herreros Martínez, Belén Pozzati, Liliana Fernández Rosáenz, Hipólito Crespo Suarez, Belén López Serrano, Pilar|||0000-0003-4488-5376 Lucendo, Alfredo J.|||0000-0003-1183-1072 Muñoz Vicente, Margarita Bermejo, Fernando|||0000-0003-4610-0886 Ramírez Palanca, José Joaquín Menacho, Margarita Carmona, Amalia Camargo, Raquel Torra Alsina, Sandra Maroto, Nuria Nerín de la Puerta, Juan Castro Ortiz, Elena Marín Jiménez, Ignacio|||0000-0001-5424-2484 Botella, Belén Sapiña, Amparo Cruz, Noelia Forcelledo, José Luis F. Bouhmidi, Abdel Castaño-Milla, Carlos Opio, Verónica Nicolás, Isabel Kutz, Marcos Abraldes Bechiarelli, Alfredo Gordillo, Jordi|||0000-0001-6418-0715 Ber, Yolanda|||0000-0002-5184-8349 Torres Domínguez, Yolanda Novella Durán, María Teresa Rodríguez Mondéjar, Silvia Martínez-Cerezo, Francisco J. Kolle, Lilyan Ledezma, Cesar Iyo, Eduardo Roncero, Oscar Irisarri, Rebeca Lluis, Laia Blázquez Gómez, Isabel Zapata, Eva María José Alcalá, María Martínez Pascual, Cristina Montealegre, María Mata, Laura Monrobel, Ana Hernández Camba, Alejandro|||0000-0002-8653-207X Hernández Villalba, Luis|||0000-0002-9175-4312 Tejada, María Mir, Alberto Galve, María Luisa Soler Rodríguez, Marta Hervías, Daniel Gómez-Valero, José Antonio Barreiro de-Acosta, Manuel|||0000-0001-5915-1477 Rodríguez-Artalejo, Fernando|||0000-0001-9317-5755 García-Esquinas, Esther|||0000-0002-8688-5174 P. Gisbert, Javier|||0000-0003-2090-3445 |
| author2_role |
author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author |
| dc.contributor.none.fl_str_mv |
Universitat Autònoma de Barcelona |
| dc.subject.none.fl_str_mv |
Epidemiology Incidence Inflammatory bowel disease Crohn's disease Ulcerative colitis |
| topic |
Epidemiology Incidence Inflammatory bowel disease Crohn's disease Ulcerative colitis |
| description |
(1) Aims: To assess the incidence of inflammatory bowel disease (IBD) in Spain, to describe the main epidemiological and clinical characteristics at diagnosis and the evolution of the disease, and to explore the use of drug treatments. (2) Methods: Prospective, population-based nationwide registry. Adult patients diagnosed with IBD-Crohn's disease (CD), ulcerative colitis (UC) or IBD unclassified (IBD-U)-during 2017 in Spain were included and were followed-up for 1 year. (3) Results: We identified 3611 incident cases of IBD diagnosed during 2017 in 108 hospitals covering over 22 million inhabitants. The overall incidence (cases/100,000 person-years) was 16 for IBD, 7.5 for CD, 8 for UC, and 0.5 for IBD-U; 53% of patients were male and median age was 43 years (interquartile range = 31-56 years). During a median 12-month follow-up, 34% of patients were treated with systemic steroids, 25% with immunomodulators, 15% with biologics and 5.6% underwent surgery. The percentage of patients under these treatments was significantly higher in CD than UC and IBD-U. Use of systemic steroids and biologics was significantly higher in hospitals with high resources. In total, 28% of patients were hospitalized (35% CD and 22% UC patients, p < 0.01). (4) Conclusion: The incidence of IBD in Spain is rather high and similar to that reported in Northern Europe. IBD patients require substantial therapeutic resources, which are greater in CD and in hospitals with high resources, and much higher than previously reported. One third of patients are hospitalized in the first year after diagnosis and a relevant proportion undergo surgery. |
| publishDate |
2021 |
| dc.date.none.fl_str_mv |
2 2021-01-01 2021 2021-01-01 |
| dc.type.none.fl_str_mv |
Article http://purl.org/coar/resource_type/c_6501 VoR http://purl.org/coar/version/c_970fb48d4fbd8a85 |
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info:eu-repo/semantics/article |
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article |
| dc.identifier.none.fl_str_mv |
https://ddd.uab.cat/record/256468 https://dx.doi.org/urn:doi:10.3390/jcm10132885 |
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https://ddd.uab.cat/record/256468 https://dx.doi.org/urn:doi:10.3390/jcm10132885 |
| dc.language.none.fl_str_mv |
Inglés eng |
| language_invalid_str_mv |
Inglés |
| language |
eng |
| dc.rights.none.fl_str_mv |
open access http://purl.org/coar/access_right/c_abf2 https://creativecommons.org/licenses/by/4.0/ |
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info:eu-repo/semantics/openAccess |
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open access http://purl.org/coar/access_right/c_abf2 https://creativecommons.org/licenses/by/4.0/ |
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openAccess |
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application/pdf |
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reponame:Dipòsit Digital de Documents de la UAB instname:Universitat Autònoma de Barcelona |
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Universitat Autònoma de Barcelona |
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Dipòsit Digital de Documents de la UAB |
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Incidence, Clinical Characteristics and Management of Inflammatory Bowel Disease in SpainLarge-Scale Epidemiological StudyChaparro, María|||0000-0002-9275-4242Garre, AnaNúñez Ortiz, AndreaDiz-Lois Palomares, María TeresaRodríguez Gutiérrez, Cristina|||0000-0003-3954-0736Riestra, Sabino|||0000-0002-9383-3698Vela, Milagros|||0000-0003-4537-9133Benítez, José Manuel|||0000-0001-8898-3141Fernández Salgado, EstelaSánchez Rodríguez, EugeniaHernández, Vicent|||0000-0003-1607-0831Ferreiro Iglesias, Rocío|||0000-0002-0469-4332Ponferrada Díaz, Ángel|||0000-0002-1176-276XBarrio, Jesús|||0000-0001-7087-3921Huguet, José María|||0000-0001-6486-1262Sicilia Aladrén, Beatriz|||0000-0002-4495-9358Martín-Arranz, María Dolores|||0000-0002-1872-0917Calvet, Xavier|||0000-0002-6278-9663Ginard, DanielAlonso-Abreu, Inmaculada|||0000-0003-0406-029XFernández-Salazar, Luis|||0000-0002-9951-7979Varela Trastoy, PilarRivero, Montserrat|||0000-0002-5834-1559Vera-Mendoza, IsabelVega Villaamil, Pablo|||0000-0001-7545-6297Navarro, Pablo|||0000-0001-6228-3462Sierra Ausín, Mónica|||0000-0003-3342-8209Cabriada, José Luis|||0000-0002-3068-5659Aguas, Mariam|||0000-0003-4353-569XVicente, Raquel|||0000-0002-7605-3534Navarro-Llavat, Mercè|||0000-0002-1132-0427Echarri, Ana|||0000-0001-6690-7543Gomollón, Fernando|||0000-0003-0076-3529Guerra del Río, ElenaPiñero, ConcepciónCasanova, María José|||0000-0001-8233-9638Spicakova, KaterinaOrtiz de Zarate, JoneTorrella Cortés, EmilioGutiérrez Casbas, Ana|||0000-0002-5460-4139Alonso-Galán, HoracioHernández-Martínez, ÁlvaroMarrero, José Miguel|||0000-0001-9445-3921Lorente Poyatos, Rufo|||0000-0003-0709-2932Calafat, Margalida|||0000-0003-2335-3792Martí Romero, LidiaRobledo, PilarBosch, OrencioJiménez, NuriaEsteve, Maria|||0000-0001-7716-0027Duque, José MaríaFuentes Coronel, Ana María|||0000-0001-8862-0922Josefa Sampedro, ManuelaSesé Abizanda, EvaHerreros Martínez, BelénPozzati, LilianaFernández Rosáenz, HipólitoCrespo Suarez, BelénLópez Serrano, Pilar|||0000-0003-4488-5376Lucendo, Alfredo J.|||0000-0003-1183-1072Muñoz Vicente, MargaritaBermejo, Fernando|||0000-0003-4610-0886Ramírez Palanca, José JoaquínMenacho, MargaritaCarmona, AmaliaCamargo, RaquelTorra Alsina, SandraMaroto, NuriaNerín de la Puerta, JuanCastro Ortiz, ElenaMarín Jiménez, Ignacio|||0000-0001-5424-2484Botella, BelénSapiña, AmparoCruz, NoeliaForcelledo, José Luis F.Bouhmidi, AbdelCastaño-Milla, CarlosOpio, VerónicaNicolás, IsabelKutz, MarcosAbraldes Bechiarelli, AlfredoGordillo, Jordi|||0000-0001-6418-0715Ber, Yolanda|||0000-0002-5184-8349Torres Domínguez, YolandaNovella Durán, María TeresaRodríguez Mondéjar, SilviaMartínez-Cerezo, Francisco J.Kolle, LilyanLedezma, CesarIyo, EduardoRoncero, OscarIrisarri, RebecaLluis, LaiaBlázquez Gómez, IsabelZapata, Eva MaríaJosé Alcalá, MaríaMartínez Pascual, CristinaMontealegre, MaríaMata, LauraMonrobel, AnaHernández Camba, Alejandro|||0000-0002-8653-207XHernández Villalba, Luis|||0000-0002-9175-4312Tejada, MaríaMir, AlbertoGalve, María LuisaSoler Rodríguez, MartaHervías, DanielGómez-Valero, José AntonioBarreiro de-Acosta, Manuel|||0000-0001-5915-1477Rodríguez-Artalejo, Fernando|||0000-0001-9317-5755García-Esquinas, Esther|||0000-0002-8688-5174P. Gisbert, Javier|||0000-0003-2090-3445EpidemiologyIncidenceInflammatory bowel diseaseCrohn's diseaseUlcerative colitis(1) Aims: To assess the incidence of inflammatory bowel disease (IBD) in Spain, to describe the main epidemiological and clinical characteristics at diagnosis and the evolution of the disease, and to explore the use of drug treatments. (2) Methods: Prospective, population-based nationwide registry. Adult patients diagnosed with IBD-Crohn's disease (CD), ulcerative colitis (UC) or IBD unclassified (IBD-U)-during 2017 in Spain were included and were followed-up for 1 year. (3) Results: We identified 3611 incident cases of IBD diagnosed during 2017 in 108 hospitals covering over 22 million inhabitants. The overall incidence (cases/100,000 person-years) was 16 for IBD, 7.5 for CD, 8 for UC, and 0.5 for IBD-U; 53% of patients were male and median age was 43 years (interquartile range = 31-56 years). During a median 12-month follow-up, 34% of patients were treated with systemic steroids, 25% with immunomodulators, 15% with biologics and 5.6% underwent surgery. The percentage of patients under these treatments was significantly higher in CD than UC and IBD-U. Use of systemic steroids and biologics was significantly higher in hospitals with high resources. In total, 28% of patients were hospitalized (35% CD and 22% UC patients, p < 0.01). (4) Conclusion: The incidence of IBD in Spain is rather high and similar to that reported in Northern Europe. IBD patients require substantial therapeutic resources, which are greater in CD and in hospitals with high resources, and much higher than previously reported. One third of patients are hospitalized in the first year after diagnosis and a relevant proportion undergo surgery.Universitat Autònoma de Barcelona 22021-01-0120212021-01-01Articlehttp://purl.org/coar/resource_type/c_6501VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfhttps://ddd.uab.cat/record/256468https://dx.doi.org/urn:doi:10.3390/jcm10132885reponame:Dipòsit Digital de Documents de la UABinstname:Universitat Autònoma de BarcelonaInglésengopen accesshttp://purl.org/coar/access_right/c_abf2Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.https://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:ddd.uab.cat:2564682026-06-06T12:50:31Z |
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15,300724 |