Structure, bioactivity and synthesis of natural products with hexahydropyrrolo[2,3-b]indole

Research on natural products containing hexahydropyrrolo[2,3-b]indole (HPI) has dramatically increased during the past few years. Newly discovered natural products with complex structures and important biological activities have recently been isolated and synthesized. This review summarizes the stru...

Full description

Bibliographic Details
Authors: Ruiz Sanchis, Pau, Savina, Svetlana A., Albericio Palomera, Fernando, Álvarez Domingo, Mercedes
Format: article
Status:Versión enviada para evaluación y publicación
Publication Date:2011
Country:España
Institution:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repository:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/55003
Online Access:https://hdl.handle.net/2445/55003
Access Level:Open access
Keyword:Alcaloides
Química heterocíclica
Productes naturals
Pèptids
Alkaloids
Heterocyclic chemistry
Natural products
Peptides
Description
Summary:Research on natural products containing hexahydropyrrolo[2,3-b]indole (HPI) has dramatically increased during the past few years. Newly discovered natural products with complex structures and important biological activities have recently been isolated and synthesized. This review summarizes the structures, biological activities, and synthetic routes for natural compounds containing HPI, emphasizing the different strategies for assembling this motif. It covers a broad gamut of molecules, from small alkaloids to complex peptides.