Orthogonal protecting groups in the synthesis of tryptophanyl-hexahydropyrroloindoles
The synthesis of various polycyclic systems containing a C3a-Ni bond between a hexahydropyrrolo[2,3-b]indole and an indole tryptophan is described here. A series of experiments were performed to determine the best combination of five orthogonal protecting groups and the best reaction conditions for...
| Autores: | , , , , |
|---|---|
| Tipo de recurso: | artículo |
| Estado: | Versión enviada para evaluación y publicación |
| Fecha de publicación: | 2011 |
| País: | España |
| Institución: | Universidad de Barcelona |
| Repositorio: | Dipòsit Digital de la UB |
| OAI Identifier: | oai:diposit.ub.edu:2445/54707 |
| Acceso en línea: | https://hdl.handle.net/2445/54707 |
| Access Level: | acceso abierto |
| Palabra clave: | Productes naturals marins Química heterocíclica Aminoàcids Síntesi de pèptids Marine natural products Heterocyclic chemistry Amino acids Peptide synthesis |
| Sumario: | The synthesis of various polycyclic systems containing a C3a-Ni bond between a hexahydropyrrolo[2,3-b]indole and an indole tryptophan is described here. A series of experiments were performed to determine the best combination of five orthogonal protecting groups and the best reaction conditions for formation of said bond, which is a common feature among many recently discovered marine natural products. |
|---|