Extracellular Vesicle-Mediated Communication between the Glioblastoma and Its Microenvironment

The glioblastoma is the most malignant form of brain cancer. Glioblastoma cells use multiple ways of communication with the tumor microenvironment in order to tune it for their own benefit. Among these, extracellular vesicles have emerged as a focus of study in the last few years. Extracellular vesi...

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Detalles Bibliográficos
Autores: Rodríguez Matarredona, Esperanza, Pastor Loro, Ángel Manuel
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2019
País:España
Institución:Universidad de Sevilla (US)
Repositorio:idUS. Depósito de Investigación de la Universidad de Sevilla
OAI Identifier:oai:idus.us.es:11441/93239
Acceso en línea:https://hdl.handle.net/11441/93239
https://doi.org/10.3390/cells9010096
Access Level:acceso abierto
Palabra clave:tumor microenvironment
exosomes
microvesicles
glioma stem cells
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spelling Extracellular Vesicle-Mediated Communication between the Glioblastoma and Its MicroenvironmentRodríguez Matarredona, EsperanzaPastor Loro, Ángel Manueltumor microenvironmentexosomesmicrovesiclesglioma stem cellsThe glioblastoma is the most malignant form of brain cancer. Glioblastoma cells use multiple ways of communication with the tumor microenvironment in order to tune it for their own benefit. Among these, extracellular vesicles have emerged as a focus of study in the last few years. Extracellular vesicles contain soluble proteins, DNA, mRNA and non-coding RNAs with which they can modulate the phenotypes of recipient cells. In this review we summarize recent findings on the extracellular vesicles-mediated bilateral communication established between glioblastoma cells and their tumor microenvironment, and the impact of this dialogue for tumor progression and recurrence.España MINECO grant number PGC2018-094654-B-100MDPIFisiología2019info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/pdfhttps://hdl.handle.net/11441/93239https://doi.org/10.3390/cells9010096reponame:idUS. Depósito de Investigación de la Universidad de Sevillainstname:Universidad de Sevilla (US)InglésCells, 9 (1), 1-13.PGC2018-094654-B-100https://doi.org/10.3390/cells9010096info:eu-repo/semantics/openAccessoai:idus.us.es:11441/932392026-06-17T12:51:07Z
dc.title.none.fl_str_mv Extracellular Vesicle-Mediated Communication between the Glioblastoma and Its Microenvironment
title Extracellular Vesicle-Mediated Communication between the Glioblastoma and Its Microenvironment
spellingShingle Extracellular Vesicle-Mediated Communication between the Glioblastoma and Its Microenvironment
Rodríguez Matarredona, Esperanza
tumor microenvironment
exosomes
microvesicles
glioma stem cells
title_short Extracellular Vesicle-Mediated Communication between the Glioblastoma and Its Microenvironment
title_full Extracellular Vesicle-Mediated Communication between the Glioblastoma and Its Microenvironment
title_fullStr Extracellular Vesicle-Mediated Communication between the Glioblastoma and Its Microenvironment
title_full_unstemmed Extracellular Vesicle-Mediated Communication between the Glioblastoma and Its Microenvironment
title_sort Extracellular Vesicle-Mediated Communication between the Glioblastoma and Its Microenvironment
dc.creator.none.fl_str_mv Rodríguez Matarredona, Esperanza
Pastor Loro, Ángel Manuel
author Rodríguez Matarredona, Esperanza
author_facet Rodríguez Matarredona, Esperanza
Pastor Loro, Ángel Manuel
author_role author
author2 Pastor Loro, Ángel Manuel
author2_role author
dc.contributor.none.fl_str_mv Fisiología
dc.subject.none.fl_str_mv tumor microenvironment
exosomes
microvesicles
glioma stem cells
topic tumor microenvironment
exosomes
microvesicles
glioma stem cells
description The glioblastoma is the most malignant form of brain cancer. Glioblastoma cells use multiple ways of communication with the tumor microenvironment in order to tune it for their own benefit. Among these, extracellular vesicles have emerged as a focus of study in the last few years. Extracellular vesicles contain soluble proteins, DNA, mRNA and non-coding RNAs with which they can modulate the phenotypes of recipient cells. In this review we summarize recent findings on the extracellular vesicles-mediated bilateral communication established between glioblastoma cells and their tumor microenvironment, and the impact of this dialogue for tumor progression and recurrence.
publishDate 2019
dc.date.none.fl_str_mv 2019
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/11441/93239
https://doi.org/10.3390/cells9010096
url https://hdl.handle.net/11441/93239
https://doi.org/10.3390/cells9010096
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Cells, 9 (1), 1-13.
PGC2018-094654-B-100
https://doi.org/10.3390/cells9010096
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:idUS. Depósito de Investigación de la Universidad de Sevilla
instname:Universidad de Sevilla (US)
instname_str Universidad de Sevilla (US)
reponame_str idUS. Depósito de Investigación de la Universidad de Sevilla
collection idUS. Depósito de Investigación de la Universidad de Sevilla
repository.name.fl_str_mv
repository.mail.fl_str_mv
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