Generation of bioactive peptides during food processing

Large amounts of peptides are naturally generated in foods through the proteolysis phenomena taking place during processing. Such proteolysis is carried out either by endogenous enzymes in ripened foods or by the combined action of endogenous and microbial enzymes when fermented. Food proteins can a...

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Detalles Bibliográficos
Autores: Toldrá Vilardell, Fidel, Reig, Milagro, Aristoy, María Concepción, Mora, Leticia
Tipo de recurso: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2017
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/166570
Acceso en línea:http://hdl.handle.net/10261/166570
Access Level:acceso abierto
Palabra clave:Bioactive peptides
Proteomics
Proteolysis
Peptides
Enzymes
Peptidases
Exo-peptidases
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spelling Generation of bioactive peptides during food processingToldrá Vilardell, FidelReig, MilagroAristoy, María ConcepciónMora, LeticiaBioactive peptidesProteomicsProteolysisPeptidesEnzymesPeptidasesExo-peptidasesLarge amounts of peptides are naturally generated in foods through the proteolysis phenomena taking place during processing. Such proteolysis is carried out either by endogenous enzymes in ripened foods or by the combined action of endogenous and microbial enzymes when fermented. Food proteins can also be isolated and hydrolysed by peptidases to produce hydrolysates. endo-peptidases act first followed by the successive action of exo-peptidases (mainly, tri- and di-peptidylpeptidases, aminopeptidases and carboxypeptidases). The generated peptides may be further hydrolysed through the gastrointestinal digestion resulting in a pool of peptides with different sequences and lengths, some of them with relevant bioactivity. However, these peptides should be absorbed intact through the intestinal barrier and reach the blood stream to exert their physiological action. This manuscript is reporting the enzymatic routes and strategies followed for the generation of bioactive peptides.The research leading to these results received funding from Grant AGL2014-57367-R from the Spanish Ministry of Economy, Industry and Competitivity and FEDER funds and from the European Union 7th Framework Programme (FP7/2007-2013) under Grant Agreement 312090 (BACCHUS).Peer reviewedElsevierMinisterio de Economía y Competitividad (España)European CommissionConsejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]201820182017info:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_6501Postprintinfo:eu-repo/semantics/acceptedVersionhttp://hdl.handle.net/10261/166570reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)Inglés#PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE#info:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/AGL2014-57367-Rinfo:eu-repo/grantAgreement/EC/FP7/312090https://doi.org/10.1016/j.foodchem.2017.06.119Síinfo:eu-repo/semantics/openAccessoai:digital.csic.es:10261/1665702026-05-22T06:33:51Z
dc.title.none.fl_str_mv Generation of bioactive peptides during food processing
title Generation of bioactive peptides during food processing
spellingShingle Generation of bioactive peptides during food processing
Toldrá Vilardell, Fidel
Bioactive peptides
Proteomics
Proteolysis
Peptides
Enzymes
Peptidases
Exo-peptidases
title_short Generation of bioactive peptides during food processing
title_full Generation of bioactive peptides during food processing
title_fullStr Generation of bioactive peptides during food processing
title_full_unstemmed Generation of bioactive peptides during food processing
title_sort Generation of bioactive peptides during food processing
dc.creator.none.fl_str_mv Toldrá Vilardell, Fidel
Reig, Milagro
Aristoy, María Concepción
Mora, Leticia
author Toldrá Vilardell, Fidel
author_facet Toldrá Vilardell, Fidel
Reig, Milagro
Aristoy, María Concepción
Mora, Leticia
author_role author
author2 Reig, Milagro
Aristoy, María Concepción
Mora, Leticia
author2_role author
author
author
dc.contributor.none.fl_str_mv Ministerio de Economía y Competitividad (España)
European Commission
Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]
dc.subject.none.fl_str_mv Bioactive peptides
Proteomics
Proteolysis
Peptides
Enzymes
Peptidases
Exo-peptidases
topic Bioactive peptides
Proteomics
Proteolysis
Peptides
Enzymes
Peptidases
Exo-peptidases
description Large amounts of peptides are naturally generated in foods through the proteolysis phenomena taking place during processing. Such proteolysis is carried out either by endogenous enzymes in ripened foods or by the combined action of endogenous and microbial enzymes when fermented. Food proteins can also be isolated and hydrolysed by peptidases to produce hydrolysates. endo-peptidases act first followed by the successive action of exo-peptidases (mainly, tri- and di-peptidylpeptidases, aminopeptidases and carboxypeptidases). The generated peptides may be further hydrolysed through the gastrointestinal digestion resulting in a pool of peptides with different sequences and lengths, some of them with relevant bioactivity. However, these peptides should be absorbed intact through the intestinal barrier and reach the blood stream to exert their physiological action. This manuscript is reporting the enzymatic routes and strategies followed for the generation of bioactive peptides.
publishDate 2017
dc.date.none.fl_str_mv 2017
2018
2018
dc.type.none.fl_str_mv info:eu-repo/semantics/article
http://purl.org/coar/resource_type/c_6501
Postprint
info:eu-repo/semantics/acceptedVersion
format article
status_str acceptedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10261/166570
url http://hdl.handle.net/10261/166570
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv #PLACEHOLDER_PARENT_METADATA_VALUE#
#PLACEHOLDER_PARENT_METADATA_VALUE#
info:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/AGL2014-57367-R
info:eu-repo/grantAgreement/EC/FP7/312090
https://doi.org/10.1016/j.foodchem.2017.06.119
Sí
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC
instname:Consejo Superior de Investigaciones Científicas (CSIC)
instname_str Consejo Superior de Investigaciones Científicas (CSIC)
reponame_str DIGITAL.CSIC. Repositorio Institucional del CSIC
collection DIGITAL.CSIC. Repositorio Institucional del CSIC
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,81155

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