Recent Progress in Enzymatic Release of Peptides in Foods of Animal Origin and Assessment of Bioactivity

[EN] There is a wide variety of peptides released from food proteins that are able to exert a relevant benefit for human health, such as angiotensin-converting enzyme inhibition, antioxidant, anti-inflammatory, hypoglucemic, or antithrombotic activity, among others. This manuscript is reviewing the...

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Detalhes bibliográficos
Autores: Toldrá Vilardell, Fidel, Gallego-Ibáñez, Marta, Reig Riera, Mª Milagro, ARISTOY ALBERT, MARÍA CONCEPCIÓN, Mora Soler, Leticia
Tipo de documento: artigo
Data de publicação:2020
País:España
Recursos:Universitat Politècnica de València (UPV)
Repositório:RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
Idioma:inglês
OAI Identifier:oai:riunet.upv.es:10251/165756
Acesso em linha:https://riunet.upv.es/handle/10251/165756
Access Level:Acceso aberto
Palavra-chave:Proteolysis
Bioactive peptides
Proteomics
Mass spectrometry
Enzyme hydrolysis
Peptidases
TECNOLOGIA DE ALIMENTOS
Descrição
Resumo:[EN] There is a wide variety of peptides released from food proteins that are able to exert a relevant benefit for human health, such as angiotensin-converting enzyme inhibition, antioxidant, anti-inflammatory, hypoglucemic, or antithrombotic activity, among others. This manuscript is reviewing the recent advances on enzymatic mechanisms for the hydrolysis of proteins from foods of animal origin, including the types of enzymes and mechanisms of action involved, the strategies followed for the isolation and identification of bioactive peptides through advanced proteomic tools, and the assessment of bioactivity and its beneficial effects. Specific applications in fermented and/or ripened foods where a significant number of bioactive peptides have been reported with relevant in vivo physiological effects on laboratory rats and humans as well as the hydrolysis of animal food proteins for the production of bioactive peptides are also reviewed.