The production of reactive oxygen and nitrogen species by skeletal muscle
[EN] Skeletal muscle has been recognized as apotential source for generation of reactive oxygen and nitrogen species for morethan 20 years. Initial investigations concentrated on the potential role of mitochondria as a major source for generation of superoxide as a “by-product” of normaloxidative me...
| Autores: | , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2007 |
| País: | España |
| Institución: | Universidad de Salamanca (USAL) |
| Repositorio: | GREDOS. Repositorio Institucional de la Universidad de Salamanca |
| OAI Identifier: | oai:gredos.usal.es:10366/153916 |
| Acceso en línea: | http://hdl.handle.net/10366/153916 |
| Access Level: | acceso abierto |
| Palabra clave: | Radicals Mitochondria Reduced nicotinamide adenine dinucleotide phosphateoxidase Free Radicals 2306.09 Radicales Libres 2411.10 Fisiología del Músculo mitocondrias radicales libres |
| Sumario: | [EN] Skeletal muscle has been recognized as apotential source for generation of reactive oxygen and nitrogen species for morethan 20 years. Initial investigations concentrated on the potential role of mitochondria as a major source for generation of superoxide as a “by-product” of normaloxidative metabolism, but recent studies have identified multiple subcellular sites,where superoxide or nitric oxide are generated in regulated and controlled systemsin response to cellular stimuli. Full evaluation of the factors regulating theseprocesses and the functions of the reactive oxygen species generated are importantin understanding the redox biology of skeletal muscle. |
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