Detection of interleukin-2 is not useful for distinguishing between latent and active tuberculosis in clinical practice: a prospective cohort study.

Previous reports have identified interleukin-2 (IL-2), quantified in the supernatants of QuantiFERON(®)-TB Gold In-tube (QFT) after 72 h of incubation, as a potential biomarker for distinguishing between latent and active tuberculosis (TB). However, its validity has not been tested in an appropriate...

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Detalles Bibliográficos
Autores: Santin M, Morandeira-Rego F, Alcaide F, Rabuñal R, Anibarro L, Agüero-Balbín R, Casas-Garcia X, Pérez-Escolano E, Navarro MD, Sánchez F, Coira-Nieto A, Trigo-Daporta M, Martinez-Meñaca A, Gonzalez-Cuevas A, López-Prieto MD, Domínguez-Castellano Á, Jové N
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2016
País:España
Institución:Fundació Sant Joan de Déu
Repositorio:r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
OAI Identifier:oai:fsjd.fundanetsuite.com:p10134
Acceso en línea:https://fsjd.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=10134
Access Level:acceso abierto
Palabra clave:Active tuberculosis, Interferon-?, Interleukin-2, Latent tuberculosis infection, QuantiFERON
Descripción
Sumario:Previous reports have identified interleukin-2 (IL-2), quantified in the supernatants of QuantiFERON(®)-TB Gold In-tube (QFT) after 72 h of incubation, as a potential biomarker for distinguishing between latent and active tuberculosis (TB). However, its validity has not been tested in an appropriate clinical cohort.