Dataset: miRNA profile in colostrum exosomes of dairy ewes (F0) supplemented with methionine during the early life

Methionine supplementation during the suckling period of ewe lambs (F0) might program persistent changes on DNA methylation, thus modifying miRNA profile of colostrum exosomes during the lactation period when these animals are adults. Identifying these changes is important because may drive some eff...

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Detalles Bibliográficos
Autores: Andrés, Sonia, Giráldez, Francisco Javier, Martín, Alba, Dehnavi, Mahsa
Tipo de recurso: conjunto de datos
Fecha de publicación:2025
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/390474
Acceso en línea:http://hdl.handle.net/10261/390474
Access Level:acceso embargado
Palabra clave:Nutritional programming
Exosomes
miRNA
Dairy sheep
Colostrum
Milk
Methionine
Organoids
http://metadata.un.org/sdg/3
Ensure healthy lives and promote well-being for all at all ages
Ensure sustainable consumption and production patterns
dairy sheep
colostrum
milk
methionine
Descripción
Sumario:Methionine supplementation during the suckling period of ewe lambs (F0) might program persistent changes on DNA methylation, thus modifying miRNA profile of colostrum exosomes during the lactation period when these animals are adults. Identifying these changes is important because may drive some effects on the offspring (F1) under natural rearing conditions. The results of the present study revealed changes in miRNA profile of colostrum exosomes as a consequence of methionine supplementation during the suckling period of ewe lambs (F0).