Alzheimer's disease as an inflammatory disease

Alzheimer's disease (AD) is a neurodegenerative condition characterized by the formation of amyloid-β plaques, aggregated and hyperphosphorylated tau protein, activated microglia and neuronal cell death, ultimately leading to progressive dementia. In this short review, we focus on neuroinflamma...

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Detalhes bibliográficos
Autores: Bolós, Marta, Perea, Juan Ramón, Ávila, Jesús
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2017
País:España
Recursos:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/253665
Acesso em linha:http://hdl.handle.net/10261/253665
Access Level:acceso abierto
Palavra-chave:Alzheimer’s disease
Beta amyloid peptide
(Aβ)
Inflammation
Microglia
Tau.
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repository_id_str
spelling Alzheimer's disease as an inflammatory diseaseBolós, MartaPerea, Juan RamónÁvila, JesúsAlzheimer’s diseaseBeta amyloid peptide(Aβ)InflammationMicrogliaTau.Alzheimer's disease (AD) is a neurodegenerative condition characterized by the formation of amyloid-β plaques, aggregated and hyperphosphorylated tau protein, activated microglia and neuronal cell death, ultimately leading to progressive dementia. In this short review, we focus on neuroinflammation in AD. Specifically, we describe the participation of microglia, as well as other factors that may contribute to inflammation, in neurodegeneration.Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]2021202120172021info:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_dcae04bcPublisher's versioninfo:eu-repo/semantics/publishedVersionhttp://hdl.handle.net/10261/253665reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)Ingléshttp://dx.doi.org/10.1515/bmc-2016-0029Síinfo:eu-repo/semantics/openAccessoai:digital.csic.es:10261/2536652026-05-22T06:33:51Z
dc.title.none.fl_str_mv Alzheimer's disease as an inflammatory disease
title Alzheimer's disease as an inflammatory disease
spellingShingle Alzheimer's disease as an inflammatory disease
Bolós, Marta
Alzheimer’s disease
Beta amyloid peptide
(Aβ)
Inflammation
Microglia
Tau.
title_short Alzheimer's disease as an inflammatory disease
title_full Alzheimer's disease as an inflammatory disease
title_fullStr Alzheimer's disease as an inflammatory disease
title_full_unstemmed Alzheimer's disease as an inflammatory disease
title_sort Alzheimer's disease as an inflammatory disease
dc.creator.none.fl_str_mv Bolós, Marta
Perea, Juan Ramón
Ávila, Jesús
author Bolós, Marta
author_facet Bolós, Marta
Perea, Juan Ramón
Ávila, Jesús
author_role author
author2 Perea, Juan Ramón
Ávila, Jesús
author2_role author
author
dc.contributor.none.fl_str_mv Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]
dc.subject.none.fl_str_mv Alzheimer’s disease
Beta amyloid peptide
(Aβ)
Inflammation
Microglia
Tau.
topic Alzheimer’s disease
Beta amyloid peptide
(Aβ)
Inflammation
Microglia
Tau.
description Alzheimer's disease (AD) is a neurodegenerative condition characterized by the formation of amyloid-β plaques, aggregated and hyperphosphorylated tau protein, activated microglia and neuronal cell death, ultimately leading to progressive dementia. In this short review, we focus on neuroinflammation in AD. Specifically, we describe the participation of microglia, as well as other factors that may contribute to inflammation, in neurodegeneration.
publishDate 2017
dc.date.none.fl_str_mv 2017
2021
2021
2021
dc.type.none.fl_str_mv info:eu-repo/semantics/article
http://purl.org/coar/resource_type/c_dcae04bc
Publisher's version
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10261/253665
url http://hdl.handle.net/10261/253665
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv http://dx.doi.org/10.1515/bmc-2016-0029
Sí
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.none.fl_str_mv reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC
instname:Consejo Superior de Investigaciones Científicas (CSIC)
instname_str Consejo Superior de Investigaciones Científicas (CSIC)
reponame_str DIGITAL.CSIC. Repositorio Institucional del CSIC
collection DIGITAL.CSIC. Repositorio Institucional del CSIC
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,81155

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