Are Oxygen-Conserving Devices Effective for Correcting Exercise Hypoxemia?

BACKGROUND: Correction of exercise hypoxemia in advanced lung diseases is crucial and often challenging. However, oxygen-conserving devices have been introduced in the market with limited evidence of effectiveness. In the present study the efficacy of 2 oxygen-conserving devices, a pulse demand oxyg...

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Autores: Marti, S, Pajares, V, Morante, F, Ramon, MA, Lara, J, Ferrer, J, Guell, MR
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2013
País:España
Institución:Institut d’Investigació Biomèdica Sant Pau (IIB Sant Pau)
Repositorio:r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
OAI Identifier:oai:iibsantpau.fundanetsuite.com:p9655
Acceso en línea:https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=9655
Access Level:acceso abierto
Palabra clave:COPD
conservers
exercise test
interstitial lung disease
oxygen inhalation therapy
technology assessment
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spelling Are Oxygen-Conserving Devices Effective for Correcting Exercise Hypoxemia?Marti, SPajares, VMorante, FRamon, MALara, JFerrer, JGuell, MRCOPDconserversexercise testinterstitial lung diseaseoxygen inhalation therapytechnology assessmentBACKGROUND: Correction of exercise hypoxemia in advanced lung diseases is crucial and often challenging. However, oxygen-conserving devices have been introduced in the market with limited evidence of effectiveness. In the present study the efficacy of 2 oxygen-conserving devices, a pulse demand oxygen delivery (DOD) system and pendant reservoir cannula (PRC), were evaluated in subjects with COPD and interstitial lung disease (ILD). METHODS: A cross-sectional, crossover study included 28 COPD and 31 ILD subjects with oxygen desaturation on the 6-min walk test (average S-pO2 < 88%). Each subject underwent 3 walk tests with DOD, PRC, and continuous oxygen flow by standard nasal cannula (CFNC), in random order, taking average S-pO2 >= 90% as the resaturation criterion. RESULTS: Exercise desaturation was corrected in 79%, 79%, and 86% of COPD subjects with CFNC, DOD, and PRC, respectively, and in 77%, 61%, and 81% of ILD subjects with CFNC, DOD, and PRC, respectively. When compared to CFNC, the oxygen-conserving devices showed similar efficacy, except a lower performance for the DOD in the ILD subjects (P = .01). CONCLUSIONS: Although these oxygen-conserving devices corrected exercise hypoxemia in most COPD and ILD subjects, correction was not achieved in about 20% of the severe COPD subjects, regardless of the device, and in nearly 40% of the ILD subjects with the DOD device. These findings underscore that individualized adjustment of oxygen flow is needed for optimal correction of exercise hypoxemia, especially with a DOD in an ILD patient.DAEDALUS ENTERPRISES INC2013info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttps://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=9655Respiratory CareISSN: 00201324ISSNe: 19433654reponame:r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pauinstname:Institut d’Investigació Biomèdica Sant Pau (IIB Sant Pau)Inglésinfo:eu-repo/semantics/openAccessoai:iibsantpau.fundanetsuite.com:p96552026-06-14T12:41:47Z
dc.title.none.fl_str_mv Are Oxygen-Conserving Devices Effective for Correcting Exercise Hypoxemia?
title Are Oxygen-Conserving Devices Effective for Correcting Exercise Hypoxemia?
spellingShingle Are Oxygen-Conserving Devices Effective for Correcting Exercise Hypoxemia?
Marti, S
COPD
conservers
exercise test
interstitial lung disease
oxygen inhalation therapy
technology assessment
title_short Are Oxygen-Conserving Devices Effective for Correcting Exercise Hypoxemia?
title_full Are Oxygen-Conserving Devices Effective for Correcting Exercise Hypoxemia?
title_fullStr Are Oxygen-Conserving Devices Effective for Correcting Exercise Hypoxemia?
title_full_unstemmed Are Oxygen-Conserving Devices Effective for Correcting Exercise Hypoxemia?
title_sort Are Oxygen-Conserving Devices Effective for Correcting Exercise Hypoxemia?
dc.creator.none.fl_str_mv Marti, S
Pajares, V
Morante, F
Ramon, MA
Lara, J
Ferrer, J
Guell, MR
author Marti, S
author_facet Marti, S
Pajares, V
Morante, F
Ramon, MA
Lara, J
Ferrer, J
Guell, MR
author_role author
author2 Pajares, V
Morante, F
Ramon, MA
Lara, J
Ferrer, J
Guell, MR
author2_role author
author
author
author
author
author
dc.subject.none.fl_str_mv COPD
conservers
exercise test
interstitial lung disease
oxygen inhalation therapy
technology assessment
topic COPD
conservers
exercise test
interstitial lung disease
oxygen inhalation therapy
technology assessment
description BACKGROUND: Correction of exercise hypoxemia in advanced lung diseases is crucial and often challenging. However, oxygen-conserving devices have been introduced in the market with limited evidence of effectiveness. In the present study the efficacy of 2 oxygen-conserving devices, a pulse demand oxygen delivery (DOD) system and pendant reservoir cannula (PRC), were evaluated in subjects with COPD and interstitial lung disease (ILD). METHODS: A cross-sectional, crossover study included 28 COPD and 31 ILD subjects with oxygen desaturation on the 6-min walk test (average S-pO2 < 88%). Each subject underwent 3 walk tests with DOD, PRC, and continuous oxygen flow by standard nasal cannula (CFNC), in random order, taking average S-pO2 >= 90% as the resaturation criterion. RESULTS: Exercise desaturation was corrected in 79%, 79%, and 86% of COPD subjects with CFNC, DOD, and PRC, respectively, and in 77%, 61%, and 81% of ILD subjects with CFNC, DOD, and PRC, respectively. When compared to CFNC, the oxygen-conserving devices showed similar efficacy, except a lower performance for the DOD in the ILD subjects (P = .01). CONCLUSIONS: Although these oxygen-conserving devices corrected exercise hypoxemia in most COPD and ILD subjects, correction was not achieved in about 20% of the severe COPD subjects, regardless of the device, and in nearly 40% of the ILD subjects with the DOD device. These findings underscore that individualized adjustment of oxygen flow is needed for optimal correction of exercise hypoxemia, especially with a DOD in an ILD patient.
publishDate 2013
dc.date.none.fl_str_mv 2013
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=9655
url https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=9655
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv DAEDALUS ENTERPRISES INC
publisher.none.fl_str_mv DAEDALUS ENTERPRISES INC
dc.source.none.fl_str_mv Respiratory Care
ISSN: 00201324
ISSNe: 19433654
reponame:r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname:Institut d’Investigació Biomèdica Sant Pau (IIB Sant Pau)
instname_str Institut d’Investigació Biomèdica Sant Pau (IIB Sant Pau)
reponame_str r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
collection r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
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repository.mail.fl_str_mv
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