Replication Data for: Influence of lipid nanoparticle composition and state on the curcumin bioavailability: an in vivo approach
The dataset includes four curcumin-loaded nanoparticle formulations (CO-LLN, MG-LLN, HPO-SLN, and CN-SLN) differing by lipid type. Each formulation was characterized for particle size, ζ-potential, and physical stability. In vivo data were collected from 16 female Sprague Dawley rats divided into fo...
| Autores: | , , , , |
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| Tipo de recurso: | conjunto de datos |
| Fecha de publicación: | 2021 |
| País: | España |
| Institución: | Consorci de Serveis Universitaris de Catalunya (CSUC) |
| Repositorio: | CORA.Repositori de Dades de Recerca |
| OAI Identifier: | oai:dnet:cora.rdr____::3c0f85023aa808c099f780401b150f01 |
| Acceso en línea: | https://doi.org/10.34810/DATA2765 |
| Access Level: | acceso abierto |
| Palabra clave: | Agricultural Sciences Medicine, Health and Life Sciences Bioavailability curcuminoids Curcumin Nanoparticles lipid type lipid state Lipids |
| Sumario: | The dataset includes four curcumin-loaded nanoparticle formulations (CO-LLN, MG-LLN, HPO-SLN, and CN-SLN) differing by lipid type. Each formulation was characterized for particle size, ζ-potential, and physical stability. In vivo data were collected from 16 female Sprague Dawley rats divided into four treatment groups, each receiving 250 mg/kg curcumin orally. Biological samples included plasma, gastrointestinal segments, liver, kidney, and adipose tissues. Curcumin and its metabolites were quantified in these samples using LC-ESI–MS/MS. Overall, the dataset integrates formulation parameters, physicochemical properties, and in vivo biodistribution profiles of curcuminoids. |
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