Replication Data for: Influence of lipid nanoparticle composition and state on the curcumin bioavailability: an in vivo approach
The dataset includes four curcumin-loaded nanoparticle formulations (CO-LLN, MG-LLN, HPO-SLN, and CN-SLN) differing by lipid type. Each formulation was characterized for particle size, ζ-potential, and physical stability. In vivo data were collected from 16 female Sprague Dawley rats divided into fo...
| Autores: | , , , , |
|---|---|
| Tipo de recurso: | conjunto de datos |
| Fecha de publicación: | 2021 |
| País: | España |
| Institución: | Universitat de Lleida (UdL) |
| Repositorio: | Repositori Obert UdL |
| OAI Identifier: | oai:repositori.udl.cat:10459.1/469183 |
| Acceso en línea: | https://doi.org/10.34810/data2765 https://hdl.handle.net/10459.1/469183 |
| Access Level: | acceso abierto |
| Palabra clave: | Agricultural Sciences Medicine, Health and Life Sciences Bioavailability curcuminoids Curcumin Nanoparticles lipid type lipid state Lipids |
| Sumario: | The dataset includes four curcumin-loaded nanoparticle formulations (CO-LLN, MG-LLN, HPO-SLN, and CN-SLN) differing by lipid type. Each formulation was characterized for particle size, ζ-potential, and physical stability. In vivo data were collected from 16 female Sprague Dawley rats divided into four treatment groups, each receiving 250 mg/kg curcumin orally. Biological samples included plasma, gastrointestinal segments, liver, kidney, and adipose tissues. Curcumin and its metabolites were quantified in these samples using LC-ESI–MS/MS. Overall, the dataset integrates formulation parameters, physicochemical properties, and in vivo biodistribution profiles of curcuminoids. |
|---|