Synthesis and Characterization of a New Series of Bis(allylic-α-aminophosphonates) under Mild Reaction Conditions

Several bis(α-aminophosphonates) have been conveniently prepared in good yields using a straightforward multicomponent Kabachnik–Fields reaction between ethane 1,2-diamine or propane 1,3-diamine, diethylphosphite and aldehydes under catalyst-free conditions. The nucleophilic substitution reaction of...

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Detalhes bibliográficos
Autores: Souii, Ichrak, Sanhoury, Med Abderrahmane, Vicario Hernando, Javier, Jiménez de Aberásturi González, Xabier, Efrit, Mohamed L., M’rabet, Hedi, De los Santos Ruiz, Jesús Manuel
Formato: artículo
Fecha de publicación:2023
País:España
Recursos:Universidad del País Vasco
Repositorio:Addi. Archivo Digital para la Docencia y la Investigación
OAI Identifier:oai:addi.ehu.eus:10810/62455
Acesso em linha:http://hdl.handle.net/10810/62455
Access Level:acceso abierto
Palavra-chave:bis(α-aminophosphonates)
bis(allylic-α-aminophosphonates)
multicomponent Kabachnik–Fields reaction
nucleophilic substitution reaction
Descrição
Resumo:Several bis(α-aminophosphonates) have been conveniently prepared in good yields using a straightforward multicomponent Kabachnik–Fields reaction between ethane 1,2-diamine or propane 1,3-diamine, diethylphosphite and aldehydes under catalyst-free conditions. The nucleophilic substitution reaction of bis(α-aminophosphonates) prepared and ethyl (2-bromomethyl)acrylate under mild reaction conditions afforded an original synthetic approach to a new series of bis(allylic-α-aminophosphonates).