Virus infection speeds: theory versus experiment

In order to explain the speed of Vesicular Stomatitis Virus VSV infections, we develop a simple model that improves previous approaches to the propagation of virus infections. For VSV infections, we find that the delay time elapsed between the adsorption of a viral particle into a cell and the relea...

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Detalles Bibliográficos
Autores: Amor, Daniel R., Fort, Joaquim
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2010
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:10256/3534
Acceso en línea:http://hdl.handle.net/10256/3534
Access Level:acceso abierto
Palabra clave:Estomatitis vesicular -- Models matemàtics
Models matemàtics
Virosis -- Models matemàtics
Mathematical models
Vesicular stomatitis -- Mathematical models
Virus diseases -- Mathematical models
Descripción
Sumario:In order to explain the speed of Vesicular Stomatitis Virus VSV infections, we develop a simple model that improves previous approaches to the propagation of virus infections. For VSV infections, we find that the delay time elapsed between the adsorption of a viral particle into a cell and the release of its progeny has a very important effect. Moreover, this delay time makes the adsorption rate essentially irrelevant in order to predict VSV infection speeds. Numerical simulations are in agreement with the analytical results. Our model satisfactorily explains the experimentally measured speeds of VSV infections