Bimodal Nd-doped luVo4 nanoprobes functionalized with polyacrilic acid for x-ray computed tomography and NIR luminescent imaging

Uniform Nd3+-doped LuVO4 nanophosphors have been synthesized for the first time in literature by using a poliol-based method at 120 °C from Nd3+ and vanadate precursors. After optimizing the Nd doping level, these phosphors present intense luminescence in the near-infrared biological windows. The X-...

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Autores: Nuñez, Nuria O., Cussó Pérez, Fernando, Cantelar Alcaide, Eugenio Francisco, Martin-gracia, Beatriz, de la Fuente, Jesús M., Corral, Ariadna, Balcerzyk, Marcin, Ocaña, Manuel
Tipo de recurso: artículo
Fecha de publicación:2020
País:España
Institución:Universidad Autónoma de Madrid
Repositorio:Biblos-e Archivo. Repositorio Institucional de la UAM
Idioma:inglés
OAI Identifier:oai:repositorio.uam.es:10486/691082
Acceso en línea:http://hdl.handle.net/10486/691082
https://dx.doi.org/10.3390/nano10010149
Access Level:acceso abierto
Palabra clave:LuVO4
Nanoparticles
Neodymium
NIR luminescence
Polyacrilic acid
X-ray computed tomography
Física
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spelling Bimodal Nd-doped luVo4 nanoprobes functionalized with polyacrilic acid for x-ray computed tomography and NIR luminescent imagingNuñez, Nuria O.Cussó Pérez, FernandoCantelar Alcaide, Eugenio FranciscoMartin-gracia, Beatrizde la Fuente, Jesús M.Corral, AriadnaBalcerzyk, MarcinOcaña, ManuelLuVO4NanoparticlesNeodymiumNIR luminescencePolyacrilic acidX-ray computed tomographyFísicaUniform Nd3+-doped LuVO4 nanophosphors have been synthesized for the first time in literature by using a poliol-based method at 120 °C from Nd3+ and vanadate precursors. After optimizing the Nd doping level, these phosphors present intense luminescence in the near-infrared biological windows. The X-ray attenuation capacity of the optimum nanophosphor has been found to be higher than that of a commercial X-ray computed tomography contrast agent. After surface coating with polyacrylic acid, such nanoparticles present high colloidal stability in physiological pH medium and high cell viability. Because of these properties, the developed Nd3+-doped LuVO4 nanoparticles have potential applications as a bimodal probe for NIR luminescent bioimaging and X-ray computed tomographyThis work has been supported by the Spanish Ministry of Science, Innovation and Universities (MCIU/AEI/FEDER) under grant RTI2018-094426-B-I00, and Ministerio de Economía y Competitividad (MINECO) under project MAT2016-75716-C2-2-RM D P I AGDepartamento de Física de MaterialesFacultad de Ciencias20202020-01-01research articlehttp://purl.org/coar/resource_type/c_2df8fbb1VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10486/691082https://dx.doi.org/10.3390/nano10010149reponame:Biblos-e Archivo. Repositorio Institucional de la UAMinstname:Universidad Autónoma de MadridInglésengopen accesshttp://purl.org/coar/access_right/c_abf2info:eu-repo/semantics/openAccessoai:repositorio.uam.es:10486/6910822026-06-23T12:46:27Z
dc.title.none.fl_str_mv Bimodal Nd-doped luVo4 nanoprobes functionalized with polyacrilic acid for x-ray computed tomography and NIR luminescent imaging
title Bimodal Nd-doped luVo4 nanoprobes functionalized with polyacrilic acid for x-ray computed tomography and NIR luminescent imaging
spellingShingle Bimodal Nd-doped luVo4 nanoprobes functionalized with polyacrilic acid for x-ray computed tomography and NIR luminescent imaging
Nuñez, Nuria O.
LuVO4
Nanoparticles
Neodymium
NIR luminescence
Polyacrilic acid
X-ray computed tomography
Física
title_short Bimodal Nd-doped luVo4 nanoprobes functionalized with polyacrilic acid for x-ray computed tomography and NIR luminescent imaging
title_full Bimodal Nd-doped luVo4 nanoprobes functionalized with polyacrilic acid for x-ray computed tomography and NIR luminescent imaging
title_fullStr Bimodal Nd-doped luVo4 nanoprobes functionalized with polyacrilic acid for x-ray computed tomography and NIR luminescent imaging
title_full_unstemmed Bimodal Nd-doped luVo4 nanoprobes functionalized with polyacrilic acid for x-ray computed tomography and NIR luminescent imaging
title_sort Bimodal Nd-doped luVo4 nanoprobes functionalized with polyacrilic acid for x-ray computed tomography and NIR luminescent imaging
dc.creator.none.fl_str_mv Nuñez, Nuria O.
Cussó Pérez, Fernando
Cantelar Alcaide, Eugenio Francisco
Martin-gracia, Beatriz
de la Fuente, Jesús M.
Corral, Ariadna
Balcerzyk, Marcin
Ocaña, Manuel
author Nuñez, Nuria O.
author_facet Nuñez, Nuria O.
Cussó Pérez, Fernando
Cantelar Alcaide, Eugenio Francisco
Martin-gracia, Beatriz
de la Fuente, Jesús M.
Corral, Ariadna
Balcerzyk, Marcin
Ocaña, Manuel
author_role author
author2 Cussó Pérez, Fernando
Cantelar Alcaide, Eugenio Francisco
Martin-gracia, Beatriz
de la Fuente, Jesús M.
Corral, Ariadna
Balcerzyk, Marcin
Ocaña, Manuel
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Departamento de Física de Materiales
Facultad de Ciencias
dc.subject.none.fl_str_mv LuVO4
Nanoparticles
Neodymium
NIR luminescence
Polyacrilic acid
X-ray computed tomography
Física
topic LuVO4
Nanoparticles
Neodymium
NIR luminescence
Polyacrilic acid
X-ray computed tomography
Física
description Uniform Nd3+-doped LuVO4 nanophosphors have been synthesized for the first time in literature by using a poliol-based method at 120 °C from Nd3+ and vanadate precursors. After optimizing the Nd doping level, these phosphors present intense luminescence in the near-infrared biological windows. The X-ray attenuation capacity of the optimum nanophosphor has been found to be higher than that of a commercial X-ray computed tomography contrast agent. After surface coating with polyacrylic acid, such nanoparticles present high colloidal stability in physiological pH medium and high cell viability. Because of these properties, the developed Nd3+-doped LuVO4 nanoparticles have potential applications as a bimodal probe for NIR luminescent bioimaging and X-ray computed tomography
publishDate 2020
dc.date.none.fl_str_mv 2020
2020-01-01
dc.type.none.fl_str_mv research article
http://purl.org/coar/resource_type/c_2df8fbb1
VoR
http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv http://hdl.handle.net/10486/691082
https://dx.doi.org/10.3390/nano10010149
url http://hdl.handle.net/10486/691082
https://dx.doi.org/10.3390/nano10010149
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv M D P I AG
publisher.none.fl_str_mv M D P I AG
dc.source.none.fl_str_mv reponame:Biblos-e Archivo. Repositorio Institucional de la UAM
instname:Universidad Autónoma de Madrid
instname_str Universidad Autónoma de Madrid
reponame_str Biblos-e Archivo. Repositorio Institucional de la UAM
collection Biblos-e Archivo. Repositorio Institucional de la UAM
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,301603

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