Emotional and cognitive effects of menopause and hormone replacement therapy

[Background] Menopause is a natural physiological process, but its effects on the brain remain poorly understood. In England, approximately 15% of women use hormone-replacement therapy (HRT) to manage menopausal symptoms. However, the psychological benefits of HRT are not well established. This stud...

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Detalles Bibliográficos
Autores: Zuhlsdorff, Katharina, Langley, Christelle, Bethlehem, Richard, Warrier, Varun, Romero García, Rafael, Sahakian, Barbara J.
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2026
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/422413
Acceso en línea:http://hdl.handle.net/10261/422413
https://api.elsevier.com/content/abstract/scopus_id/105028662587
Access Level:acceso abierto
Palabra clave:Anterior cingulate cortex
Cognition
Entorhinal cortex
Hippocampus
Hormone replacement therapy
Menopause
Mental health
Descripción
Sumario:[Background] Menopause is a natural physiological process, but its effects on the brain remain poorly understood. In England, approximately 15% of women use hormone-replacement therapy (HRT) to manage menopausal symptoms. However, the psychological benefits of HRT are not well established. This study aims to investigate the impact of menopause and HRT on mental health, cognitive function, and brain structure.