Study of the geometry in a 3D flow‑focusing device

We present a numerical and experimental study on a non-planar three-dimensional design of a microfluidic flow-focusing device for the well-controlled generation of monodisperse micron-sized droplets. Three relevant geometric parameters were identified: the distance between the inner inlet channel an...

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Authors: Castro Hernández, Elena De, Kok, Maarten P., Versluis, Michel, Fernández Rivas, David
Format: article
Status:Published version
Publication Date:2016
Country:España
Institution:Universidad de Sevilla (US)
Repository:idUS. Depósito de Investigación de la Universidad de Sevilla
OAI Identifier:oai:idus.us.es:11441/135011
Online Access:https://hdl.handle.net/11441/135011
https://doi.org/10.1007/s10404-016-1708-3
Access Level:Open access
Keyword:Flow-focusing
Microfluidics
Jet
Micro-droplets
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spelling Study of the geometry in a 3D flow‑focusing deviceCastro Hernández, Elena DeKok, Maarten P.Versluis, MichelFernández Rivas, DavidFlow-focusingMicrofluidicsJetMicro-dropletsWe present a numerical and experimental study on a non-planar three-dimensional design of a microfluidic flow-focusing device for the well-controlled generation of monodisperse micron-sized droplets. Three relevant geometric parameters were identified: the distance between the inner inlet channel and the outlet channel, the width of the outlet channel, and its length. Simulation data extracted from a full parameter study and finite element simulations yielded four optimum designs that were then fabricated using soft lithography techniques. Under the predicted operating conditions, micro-droplets of a size of ~1μm in diameter are obtained from a channel 50 μm in width. This work represents an important breakthrough in the practical use of flow-focusing devices delivering a ratio of constriction to droplet size of 50 times, with the advantage of reduced clogging of the micro-channel, greatly improving the control and reliability of the device.Consejería de Innovación, Ciencia y Empresa P10-TEP-5984SpringerIngeniería Aeroespacial y Mecánica de FluidosJunta de Andalucía2016info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/pdfhttps://hdl.handle.net/11441/135011https://doi.org/10.1007/s10404-016-1708-3reponame:idUS. Depósito de Investigación de la Universidad de Sevillainstname:Universidad de Sevilla (US)InglésMicrofluidics and Nanofluidics, 20 (2), 40.P10-TEP-5984https://dx.doi.org/10.1007/s10404-016-1708-3info:eu-repo/semantics/openAccessoai:idus.us.es:11441/1350112026-06-17T12:51:07Z
dc.title.none.fl_str_mv Study of the geometry in a 3D flow‑focusing device
title Study of the geometry in a 3D flow‑focusing device
spellingShingle Study of the geometry in a 3D flow‑focusing device
Castro Hernández, Elena De
Flow-focusing
Microfluidics
Jet
Micro-droplets
title_short Study of the geometry in a 3D flow‑focusing device
title_full Study of the geometry in a 3D flow‑focusing device
title_fullStr Study of the geometry in a 3D flow‑focusing device
title_full_unstemmed Study of the geometry in a 3D flow‑focusing device
title_sort Study of the geometry in a 3D flow‑focusing device
dc.creator.none.fl_str_mv Castro Hernández, Elena De
Kok, Maarten P.
Versluis, Michel
Fernández Rivas, David
author Castro Hernández, Elena De
author_facet Castro Hernández, Elena De
Kok, Maarten P.
Versluis, Michel
Fernández Rivas, David
author_role author
author2 Kok, Maarten P.
Versluis, Michel
Fernández Rivas, David
author2_role author
author
author
dc.contributor.none.fl_str_mv Ingeniería Aeroespacial y Mecánica de Fluidos
Junta de Andalucía
dc.subject.none.fl_str_mv Flow-focusing
Microfluidics
Jet
Micro-droplets
topic Flow-focusing
Microfluidics
Jet
Micro-droplets
description We present a numerical and experimental study on a non-planar three-dimensional design of a microfluidic flow-focusing device for the well-controlled generation of monodisperse micron-sized droplets. Three relevant geometric parameters were identified: the distance between the inner inlet channel and the outlet channel, the width of the outlet channel, and its length. Simulation data extracted from a full parameter study and finite element simulations yielded four optimum designs that were then fabricated using soft lithography techniques. Under the predicted operating conditions, micro-droplets of a size of ~1μm in diameter are obtained from a channel 50 μm in width. This work represents an important breakthrough in the practical use of flow-focusing devices delivering a ratio of constriction to droplet size of 50 times, with the advantage of reduced clogging of the micro-channel, greatly improving the control and reliability of the device.
publishDate 2016
dc.date.none.fl_str_mv 2016
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/11441/135011
https://doi.org/10.1007/s10404-016-1708-3
url https://hdl.handle.net/11441/135011
https://doi.org/10.1007/s10404-016-1708-3
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Microfluidics and Nanofluidics, 20 (2), 40.
P10-TEP-5984
https://dx.doi.org/10.1007/s10404-016-1708-3
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Springer
publisher.none.fl_str_mv Springer
dc.source.none.fl_str_mv reponame:idUS. Depósito de Investigación de la Universidad de Sevilla
instname:Universidad de Sevilla (US)
instname_str Universidad de Sevilla (US)
reponame_str idUS. Depósito de Investigación de la Universidad de Sevilla
collection idUS. Depósito de Investigación de la Universidad de Sevilla
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,300724

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