Primary breast cancer and health related quality of life in Spanish women: The EpiGEICAM case-control study

This study evaluates the impact of breast cancer (BC) in health related quality of life (HRQL) and in psychological distress (PD) during the initial phases of the disease and looks for contributing factors. A multicentric case-control study, EpiGEICAM, was carried out. Incident BC cases and age- and...

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Detalles Bibliográficos
Autores: Fernández de Larrea-Baz, Nerea, Pérez-Gómez, Beatriz, Guerrero-Zotano, Ángel, Casas, Ana María, Bermejo, Begoña, Baena-Cañada, José Manuel, Antolin, Silvia, Sánchez-Rovira, Pedro, Ramos Vázquez, Manuel, Garcia-Sáenz, José Ángel, Antón, Antonio, Muñoz, Montserrat, de Juan, Ana, Jara, Carlos, Chacón, José Ignacio, Arcusa, Angels, Gil-Gil, Miguel, Adrover, Encarna, Oltra, Amparo, Brunet, Joan, González, Sonia, Bezares, Susana, Lope, Virginia, Martín, Miguel, Pollán Santamaría, Marina Anunciación
Tipo de recurso: artículo
Fecha de publicación:2020
País:España
Institución:Universidad Autónoma de Madrid
Repositorio:Biblos-e Archivo. Repositorio Institucional de la UAM
Idioma:inglés
OAI Identifier:oai:repositorio.uam.es:10486/693543
Acceso en línea:http://hdl.handle.net/10486/693543
https://dx.doi.org/10.1038/s41598-020-63637-w
Access Level:acceso abierto
Palabra clave:Breast cancer
Health related quality of life (HRQL)
Psychological distress (PD)
EpiGEICAM
Medicina
Descripción
Sumario:This study evaluates the impact of breast cancer (BC) in health related quality of life (HRQL) and in psychological distress (PD) during the initial phases of the disease and looks for contributing factors. A multicentric case-control study, EpiGEICAM, was carried out. Incident BC cases and age- and residence- matched controls were included. Clinical, epidemiological, HRQL (SF-36) and PD information (GHQ-28) was collected. We used multivariable logistic regression models to estimate OR of low HRQL and of PD in cases compared to controls, and to identify factors associated with low HRQL and with PD. Among 896 BC cases and 890 control women, cases had poorer scores than both, the reference population and the control group, in all SF-36 scales. BC women with lower education, younger, active workers, never smokers, those with comorbidities, in stage IV and with surgical treatment had lower physical HRQL; factors associated with low mental HRQL were dissatisfaction with social support, being current smoker and having children. Cases had a fivefold increased odds of PD compared to controls. Managing comorbidities and trying to promote social support, especially in younger and less educated women, could improve well-being of BC patients.

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