Heart Failure after Cardiac Surgery: The Role of Halogenated Agents, Myocardial Conditioning and Oxidative Stress.

Heart disease requires a surgical approach sometimes. Cardiac-surgery patients develop heart failure associated with ischemia induced during extracorporeal circulation. This complication could be decreased with anesthetic drugs. The cardioprotective effects of halogenated agents are based on pre- an...

Descripción completa

Detalles Bibliográficos
Autores: Guerrero-Orriach, José Luis, Carmona-Luque, Maria Dolores, Gonzalez-Alvarez, Laura
Tipo de recurso: artículo
Fecha de publicación:2022
País:España
Institución:Instituto de Salud Carlos III (ISCIII)
Repositorio:Repisalud
Idioma:inglés
OAI Identifier:oai:repisalud.isciii.es:20.500.12105/18588
Acceso en línea:http://hdl.handle.net/20.500.12105/18588
Access Level:acceso abierto
Palabra clave:ACDHUVV-16
halogenated
heart failure
postconditioning
preconditioning
Anesthetics, Inhalation
Cardiac Surgical Procedures
Cardiomyopathies
Cardiotonic Agents
Heart Failure
Humans
Hydrocarbons, Halogenated
Isoflurane
Myocardium
Oxidative Stress
Propofol
Sevoflurane
id ES_831908bdbb9f58e00a0783ae89c4eeb5
oai_identifier_str oai:repisalud.isciii.es:20.500.12105/18588
network_acronym_str ES
network_name_str España
repository_id_str
spelling Heart Failure after Cardiac Surgery: The Role of Halogenated Agents, Myocardial Conditioning and Oxidative Stress.Guerrero-Orriach, José LuisCarmona-Luque, Maria DoloresGonzalez-Alvarez, LauraACDHUVV-16halogenatedheart failurepostconditioningpreconditioningAnesthetics, InhalationCardiac Surgical ProceduresCardiomyopathiesCardiotonic AgentsHeart FailureHumansHydrocarbons, HalogenatedIsofluraneMyocardiumOxidative StressPropofolSevofluraneHeart disease requires a surgical approach sometimes. Cardiac-surgery patients develop heart failure associated with ischemia induced during extracorporeal circulation. This complication could be decreased with anesthetic drugs. The cardioprotective effects of halogenated agents are based on pre- and postconditioning (sevoflurane, desflurane, or isoflurane) compared to intravenous hypnotics (propofol). We tried to put light on the shadows walking through the line of the halogenated anesthetic drugs' effects in several enzymatic routes and oxidative stress, waiting for the final results of the ACDHUVV-16 clinical trial regarding the genetic modulation of this kind of drugs.20242024-02-2720222022-01-2520222022-01-25research articlehttp://purl.org/coar/resource_type/c_2df8fbb1VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articlehttp://hdl.handle.net/20.500.12105/18588reponame:Repisaludinstname:Instituto de Salud Carlos III (ISCIII)Inglésengopen accesshttp://purl.org/coar/access_right/c_abf2Attribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:repisalud.isciii.es:20.500.12105/185882026-06-12T12:43:37Z
dc.title.none.fl_str_mv Heart Failure after Cardiac Surgery: The Role of Halogenated Agents, Myocardial Conditioning and Oxidative Stress.
title Heart Failure after Cardiac Surgery: The Role of Halogenated Agents, Myocardial Conditioning and Oxidative Stress.
spellingShingle Heart Failure after Cardiac Surgery: The Role of Halogenated Agents, Myocardial Conditioning and Oxidative Stress.
Guerrero-Orriach, José Luis
ACDHUVV-16
halogenated
heart failure
postconditioning
preconditioning
Anesthetics, Inhalation
Cardiac Surgical Procedures
Cardiomyopathies
Cardiotonic Agents
Heart Failure
Humans
Hydrocarbons, Halogenated
Isoflurane
Myocardium
Oxidative Stress
Propofol
Sevoflurane
title_short Heart Failure after Cardiac Surgery: The Role of Halogenated Agents, Myocardial Conditioning and Oxidative Stress.
title_full Heart Failure after Cardiac Surgery: The Role of Halogenated Agents, Myocardial Conditioning and Oxidative Stress.
title_fullStr Heart Failure after Cardiac Surgery: The Role of Halogenated Agents, Myocardial Conditioning and Oxidative Stress.
title_full_unstemmed Heart Failure after Cardiac Surgery: The Role of Halogenated Agents, Myocardial Conditioning and Oxidative Stress.
title_sort Heart Failure after Cardiac Surgery: The Role of Halogenated Agents, Myocardial Conditioning and Oxidative Stress.
dc.creator.none.fl_str_mv Guerrero-Orriach, José Luis
Carmona-Luque, Maria Dolores
Gonzalez-Alvarez, Laura
author Guerrero-Orriach, José Luis
author_facet Guerrero-Orriach, José Luis
Carmona-Luque, Maria Dolores
Gonzalez-Alvarez, Laura
author_role author
author2 Carmona-Luque, Maria Dolores
Gonzalez-Alvarez, Laura
author2_role author
author
dc.contributor.none.fl_str_mv
dc.subject.none.fl_str_mv ACDHUVV-16
halogenated
heart failure
postconditioning
preconditioning
Anesthetics, Inhalation
Cardiac Surgical Procedures
Cardiomyopathies
Cardiotonic Agents
Heart Failure
Humans
Hydrocarbons, Halogenated
Isoflurane
Myocardium
Oxidative Stress
Propofol
Sevoflurane
topic ACDHUVV-16
halogenated
heart failure
postconditioning
preconditioning
Anesthetics, Inhalation
Cardiac Surgical Procedures
Cardiomyopathies
Cardiotonic Agents
Heart Failure
Humans
Hydrocarbons, Halogenated
Isoflurane
Myocardium
Oxidative Stress
Propofol
Sevoflurane
description Heart disease requires a surgical approach sometimes. Cardiac-surgery patients develop heart failure associated with ischemia induced during extracorporeal circulation. This complication could be decreased with anesthetic drugs. The cardioprotective effects of halogenated agents are based on pre- and postconditioning (sevoflurane, desflurane, or isoflurane) compared to intravenous hypnotics (propofol). We tried to put light on the shadows walking through the line of the halogenated anesthetic drugs' effects in several enzymatic routes and oxidative stress, waiting for the final results of the ACDHUVV-16 clinical trial regarding the genetic modulation of this kind of drugs.
publishDate 2022
dc.date.none.fl_str_mv 2022
2022-01-25
2022
2022-01-25
2024
2024-02-27
dc.type.none.fl_str_mv research article
http://purl.org/coar/resource_type/c_2df8fbb1
VoR
http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv http://hdl.handle.net/20.500.12105/18588
url http://hdl.handle.net/20.500.12105/18588
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution 4.0 International
http://creativecommons.org/licenses/by/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution 4.0 International
http://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.source.none.fl_str_mv reponame:Repisalud
instname:Instituto de Salud Carlos III (ISCIII)
instname_str Instituto de Salud Carlos III (ISCIII)
reponame_str Repisalud
collection Repisalud
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869412109365805056
score 15,812429

Similares en LA Referencia