Risk Calculators in Bipolar Disorder: A Systematic Review

Introduction: Early recognition of bipolar disorder improves the prognosis and decreases the burden of the disease. However, there is a significant delay in diagnosis. Multiple risk factors for bipolar disorder have been identified and a population at high-risk for the disorder has been more precise...

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Autores: Silva Ribeiro, Joana, Pereira, Daniela, Salagre Muñoz, Estela, Coroa, Manuel, Santos Oliveira, Pedro, Santos, Vítor, Madeira, Nuno, Grande i Fullana, Iria, Vieta i Pascual, Eduard, 1963-
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2020
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/176668
Acceso en línea:https://hdl.handle.net/2445/176668
Access Level:acceso abierto
Palabra clave:Trastorn bipolar
Avaluació del risc per la salut
Ressenyes sistemàtiques (Investigació mèdica)
Manic-depressive illness
Health risk assessment
Systematic reviews (Medical research)
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spelling Risk Calculators in Bipolar Disorder: A Systematic ReviewSilva Ribeiro, JoanaPereira, DanielaSalagre Muñoz, EstelaCoroa, ManuelSantos Oliveira, PedroSantos, VítorMadeira, NunoGrande i Fullana, IriaVieta i Pascual, Eduard, 1963-Trastorn bipolarAvaluació del risc per la salutRessenyes sistemàtiques (Investigació mèdica)Manic-depressive illnessHealth risk assessmentSystematic reviews (Medical research)Introduction: Early recognition of bipolar disorder improves the prognosis and decreases the burden of the disease. However, there is a significant delay in diagnosis. Multiple risk factors for bipolar disorder have been identified and a population at high-risk for the disorder has been more precisely defined. These advances have allowed the development of risk calculators to predict individual risk of conversion to bipolar disorder. This review aims to identify the risk calculators for bipolar disorder and assess their clinical applicability. Methods: A systematic review of original studies on the development of risk calculators in bipolar disorder was performed. The studies' quality was evaluated with the Newcastle-Ottawa Quality Assessment Form for Cohort Studies and according to recommendations of the Transparent Reporting of a multivariable prediction model for Individual Prognosis or Diagnosis Initiative. Results: Three studies met the inclusion criteria; one developed a risk calculator of conversion from major depressive episode to bipolar disorder; one of conversion to new-onset bipolar spectrum disorders in offspring of parents with bipolar disorder; and the last one of conversion in youths with bipolar disorder not-otherwise-specified. Conclusions: The calculators reviewed in this article present good discrimination power for bipolar disorder, although future replication and validation of the models is needed.MDPI2021202120202021info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion14 p.application/pdfapplication/pdfhttps://hdl.handle.net/2445/176668Articles publicats en revistes (Medicina)reponame:Recercat. Dipósit de la Recerca de Catalunyainstname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)InglésReproducció del document publicat a: https://doi.org/10.3390/brainsci10080525Brain Sciences, 2020, vol. 10, num. 8, p. 525https://doi.org/10.3390/brainsci10080525cc-by (c) Silva Ribeiro, Joana et al., 2020http://creativecommons.org/licenses/by/3.0/esinfo:eu-repo/semantics/openAccessoai:recercat.cat:2445/1766682026-05-29T05:05:01Z
dc.title.none.fl_str_mv Risk Calculators in Bipolar Disorder: A Systematic Review
title Risk Calculators in Bipolar Disorder: A Systematic Review
spellingShingle Risk Calculators in Bipolar Disorder: A Systematic Review
Silva Ribeiro, Joana
Trastorn bipolar
Avaluació del risc per la salut
Ressenyes sistemàtiques (Investigació mèdica)
Manic-depressive illness
Health risk assessment
Systematic reviews (Medical research)
title_short Risk Calculators in Bipolar Disorder: A Systematic Review
title_full Risk Calculators in Bipolar Disorder: A Systematic Review
title_fullStr Risk Calculators in Bipolar Disorder: A Systematic Review
title_full_unstemmed Risk Calculators in Bipolar Disorder: A Systematic Review
title_sort Risk Calculators in Bipolar Disorder: A Systematic Review
dc.creator.none.fl_str_mv Silva Ribeiro, Joana
Pereira, Daniela
Salagre Muñoz, Estela
Coroa, Manuel
Santos Oliveira, Pedro
Santos, Vítor
Madeira, Nuno
Grande i Fullana, Iria
Vieta i Pascual, Eduard, 1963-
author Silva Ribeiro, Joana
author_facet Silva Ribeiro, Joana
Pereira, Daniela
Salagre Muñoz, Estela
Coroa, Manuel
Santos Oliveira, Pedro
Santos, Vítor
Madeira, Nuno
Grande i Fullana, Iria
Vieta i Pascual, Eduard, 1963-
author_role author
author2 Pereira, Daniela
Salagre Muñoz, Estela
Coroa, Manuel
Santos Oliveira, Pedro
Santos, Vítor
Madeira, Nuno
Grande i Fullana, Iria
Vieta i Pascual, Eduard, 1963-
author2_role author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Trastorn bipolar
Avaluació del risc per la salut
Ressenyes sistemàtiques (Investigació mèdica)
Manic-depressive illness
Health risk assessment
Systematic reviews (Medical research)
topic Trastorn bipolar
Avaluació del risc per la salut
Ressenyes sistemàtiques (Investigació mèdica)
Manic-depressive illness
Health risk assessment
Systematic reviews (Medical research)
description Introduction: Early recognition of bipolar disorder improves the prognosis and decreases the burden of the disease. However, there is a significant delay in diagnosis. Multiple risk factors for bipolar disorder have been identified and a population at high-risk for the disorder has been more precisely defined. These advances have allowed the development of risk calculators to predict individual risk of conversion to bipolar disorder. This review aims to identify the risk calculators for bipolar disorder and assess their clinical applicability. Methods: A systematic review of original studies on the development of risk calculators in bipolar disorder was performed. The studies' quality was evaluated with the Newcastle-Ottawa Quality Assessment Form for Cohort Studies and according to recommendations of the Transparent Reporting of a multivariable prediction model for Individual Prognosis or Diagnosis Initiative. Results: Three studies met the inclusion criteria; one developed a risk calculator of conversion from major depressive episode to bipolar disorder; one of conversion to new-onset bipolar spectrum disorders in offspring of parents with bipolar disorder; and the last one of conversion in youths with bipolar disorder not-otherwise-specified. Conclusions: The calculators reviewed in this article present good discrimination power for bipolar disorder, although future replication and validation of the models is needed.
publishDate 2020
dc.date.none.fl_str_mv 2020
2021
2021
2021
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/2445/176668
url https://hdl.handle.net/2445/176668
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Reproducció del document publicat a: https://doi.org/10.3390/brainsci10080525
Brain Sciences, 2020, vol. 10, num. 8, p. 525
https://doi.org/10.3390/brainsci10080525
dc.rights.none.fl_str_mv cc-by (c) Silva Ribeiro, Joana et al., 2020
http://creativecommons.org/licenses/by/3.0/es
info:eu-repo/semantics/openAccess
rights_invalid_str_mv cc-by (c) Silva Ribeiro, Joana et al., 2020
http://creativecommons.org/licenses/by/3.0/es
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 14 p.
application/pdf
application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv Articles publicats en revistes (Medicina)
reponame:Recercat. Dipósit de la Recerca de Catalunya
instname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
instname_str Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
reponame_str Recercat. Dipósit de la Recerca de Catalunya
collection Recercat. Dipósit de la Recerca de Catalunya
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15.812455

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