Dynamic of bacteriophages infection on either resistant or non-resistant soil bacteria

Students have learned basic microbiology techniques to understand the importance of viruses and their antiviral counterparts present in bacterial genomes. In particular, we have analyzed the dynamic of a phage infection in the presence of a defense-associated reverse transcriptase (DRT) antiviral sy...

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Detalles Bibliográficos
Autores: Pérez-Conde, A., Adriaenssens, A., Triviño, A., Salazar, P., Molero, M., Aceituno-Delgado, L., Ayerbe, J., Sánchez-Nieto, Esperanza, Martínez-Abarca, Francisco
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2024
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/368593
Acceso en línea:http://hdl.handle.net/10261/368593
Access Level:acceso abierto
Palabra clave:Sinorhizobium meliloti
Defense-associated Reverse Transcriptases (DRTs)
Phage predation
Descripción
Sumario:Students have learned basic microbiology techniques to understand the importance of viruses and their antiviral counterparts present in bacterial genomes. In particular, we have analyzed the dynamic of a phage infection in the presence of a defense-associated reverse transcriptase (DRT) antiviral system (UG5 group) found in the bacteria Sinorhizobium meliloti. The presence of the defense system affects phage replication by up to 5 orders of magnitude. Results obtained exemplified how the presence of an abortive defense system eliminates phages in the environment more efficiently than the absence of host infection.