Assessment of anti-malondialdehyde-acetaldehyde antibody frequencies in rheumatoid arthritis with new data from two independent cohorts, meta-analysis, and meta-regression

Autoantibodies are critical elements in RA pathogenesis and clinical assessment. The anti-malondialdehyde-acetaldehyde (anti-MAA) antibodies are potentially useful because of their claimed high sensitivity for all RA patients, including those lacking RF and anti-CCP antibodies. Therefore, we aimed t...

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Autores: Rodriguez-Martinez, Lorena, García-Moreno, Cristina, Perez-Pampin, Eva, Gómara Elena, María José, Sarmiento-Monroy, Juan C., Lopez-Golán, Yolanda, Gómez-Puerta, José A., Mera-Varela, Antonio, Conde, Carmen, Sanmartí, Raimon, Haro Villar, Isabel, González, Antonio
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2023
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/337414
Acceso en línea:http://hdl.handle.net/10261/337414
https://api.elsevier.com/content/abstract/scopus_id/85173315513
Access Level:acceso abierto
Palabra clave:Rheumatoid arthritis
Autoantibodies
Biomarker
Heterogeneity
Meta-analysis
Post-translational modifications
http://metadata.un.org/sdg/3
Ensure healthy lives and promote well-being for all at all ages
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spelling Assessment of anti-malondialdehyde-acetaldehyde antibody frequencies in rheumatoid arthritis with new data from two independent cohorts, meta-analysis, and meta-regressionRodriguez-Martinez, LorenaGarcía-Moreno, CristinaPerez-Pampin, EvaGómara Elena, María JoséSarmiento-Monroy, Juan C.Lopez-Golán, YolandaGómez-Puerta, José A.Mera-Varela, AntonioConde, CarmenSanmartí, RaimonHaro Villar, IsabelGonzález, AntonioRheumatoid arthritisAutoantibodiesBiomarkerHeterogeneityMeta-analysisPost-translational modificationshttp://metadata.un.org/sdg/3Ensure healthy lives and promote well-being for all at all agesAutoantibodies are critical elements in RA pathogenesis and clinical assessment. The anti-malondialdehyde-acetaldehyde (anti-MAA) antibodies are potentially useful because of their claimed high sensitivity for all RA patients, including those lacking RF and anti-CCP antibodies. Therefore, we aimed to replicate these findings.The research done in Santiago was funded by Instituto de Salud Carlos III through the projects PI20/01268, PI17/01606 and RD21/0002/0003, co-funded by the European Union. L.R.-M. was supported by Xunta de Galicia (Spain) through a Gain pre-doctoral fellowship (IN606A-2017/015). The research in Barcelona was funded by the Spanish Ministry of Economy, Industry and Competitiveness and the European Regional Development Fund (Grant PID2021-122216OB-I00).Peer reviewedBioMed Central0000-0002-9604-68330000-0002-3734-14370000-0003-0319-44560000-0002-6906-48330000-0002-8426-72680000-0001-8177-702X0000-0001-9380-69750000-0001-5717-54830000-0002-8864-38060000-0001-8677-23400000-0002-2624-0606Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]202320232023info:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_6501Publisher's versioninfo:eu-repo/semantics/publishedVersionhttp://hdl.handle.net/10261/337414https://api.elsevier.com/content/abstract/scopus_id/85173315513reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)InglésArthritis research & therapyhttps://doi.org/10.1186/s13075-023-03180-xSíinfo:eu-repo/semantics/openAccessoai:digital.csic.es:10261/3374142026-05-22T06:33:51Z
dc.title.none.fl_str_mv Assessment of anti-malondialdehyde-acetaldehyde antibody frequencies in rheumatoid arthritis with new data from two independent cohorts, meta-analysis, and meta-regression
title Assessment of anti-malondialdehyde-acetaldehyde antibody frequencies in rheumatoid arthritis with new data from two independent cohorts, meta-analysis, and meta-regression
spellingShingle Assessment of anti-malondialdehyde-acetaldehyde antibody frequencies in rheumatoid arthritis with new data from two independent cohorts, meta-analysis, and meta-regression
Rodriguez-Martinez, Lorena
Rheumatoid arthritis
Autoantibodies
Biomarker
Heterogeneity
Meta-analysis
Post-translational modifications
http://metadata.un.org/sdg/3
Ensure healthy lives and promote well-being for all at all ages
title_short Assessment of anti-malondialdehyde-acetaldehyde antibody frequencies in rheumatoid arthritis with new data from two independent cohorts, meta-analysis, and meta-regression
title_full Assessment of anti-malondialdehyde-acetaldehyde antibody frequencies in rheumatoid arthritis with new data from two independent cohorts, meta-analysis, and meta-regression
title_fullStr Assessment of anti-malondialdehyde-acetaldehyde antibody frequencies in rheumatoid arthritis with new data from two independent cohorts, meta-analysis, and meta-regression
title_full_unstemmed Assessment of anti-malondialdehyde-acetaldehyde antibody frequencies in rheumatoid arthritis with new data from two independent cohorts, meta-analysis, and meta-regression
title_sort Assessment of anti-malondialdehyde-acetaldehyde antibody frequencies in rheumatoid arthritis with new data from two independent cohorts, meta-analysis, and meta-regression
dc.creator.none.fl_str_mv Rodriguez-Martinez, Lorena
García-Moreno, Cristina
Perez-Pampin, Eva
Gómara Elena, María José
Sarmiento-Monroy, Juan C.
Lopez-Golán, Yolanda
Gómez-Puerta, José A.
Mera-Varela, Antonio
Conde, Carmen
Sanmartí, Raimon
Haro Villar, Isabel
González, Antonio
author Rodriguez-Martinez, Lorena
author_facet Rodriguez-Martinez, Lorena
García-Moreno, Cristina
Perez-Pampin, Eva
Gómara Elena, María José
Sarmiento-Monroy, Juan C.
Lopez-Golán, Yolanda
Gómez-Puerta, José A.
Mera-Varela, Antonio
Conde, Carmen
Sanmartí, Raimon
Haro Villar, Isabel
González, Antonio
author_role author
author2 García-Moreno, Cristina
Perez-Pampin, Eva
Gómara Elena, María José
Sarmiento-Monroy, Juan C.
Lopez-Golán, Yolanda
Gómez-Puerta, José A.
Mera-Varela, Antonio
Conde, Carmen
Sanmartí, Raimon
Haro Villar, Isabel
González, Antonio
author2_role author
author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv 0000-0002-9604-6833
0000-0002-3734-1437
0000-0003-0319-4456
0000-0002-6906-4833
0000-0002-8426-7268
0000-0001-8177-702X
0000-0001-9380-6975
0000-0001-5717-5483
0000-0002-8864-3806
0000-0001-8677-2340
0000-0002-2624-0606
Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]
dc.subject.none.fl_str_mv Rheumatoid arthritis
Autoantibodies
Biomarker
Heterogeneity
Meta-analysis
Post-translational modifications
http://metadata.un.org/sdg/3
Ensure healthy lives and promote well-being for all at all ages
topic Rheumatoid arthritis
Autoantibodies
Biomarker
Heterogeneity
Meta-analysis
Post-translational modifications
http://metadata.un.org/sdg/3
Ensure healthy lives and promote well-being for all at all ages
description Autoantibodies are critical elements in RA pathogenesis and clinical assessment. The anti-malondialdehyde-acetaldehyde (anti-MAA) antibodies are potentially useful because of their claimed high sensitivity for all RA patients, including those lacking RF and anti-CCP antibodies. Therefore, we aimed to replicate these findings.
publishDate 2023
dc.date.none.fl_str_mv 2023
2023
2023
dc.type.none.fl_str_mv info:eu-repo/semantics/article
http://purl.org/coar/resource_type/c_6501
Publisher's version
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10261/337414
https://api.elsevier.com/content/abstract/scopus_id/85173315513
url http://hdl.handle.net/10261/337414
https://api.elsevier.com/content/abstract/scopus_id/85173315513
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Arthritis research & therapy
https://doi.org/10.1186/s13075-023-03180-x
Sí
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv BioMed Central
publisher.none.fl_str_mv BioMed Central
dc.source.none.fl_str_mv reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC
instname:Consejo Superior de Investigaciones Científicas (CSIC)
instname_str Consejo Superior de Investigaciones Científicas (CSIC)
reponame_str DIGITAL.CSIC. Repositorio Institucional del CSIC
collection DIGITAL.CSIC. Repositorio Institucional del CSIC
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,81155

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