Assessment of anti-malondialdehyde-acetaldehyde antibody frequencies in rheumatoid arthritis with new data from two independent cohorts, meta-analysis, and meta-regression

Autoantibodies are critical elements in RA pathogenesis and clinical assessment. The anti-malondialdehyde-acetaldehyde (anti-MAA) antibodies are potentially useful because of their claimed high sensitivity for all RA patients, including those lacking RF and anti-CCP antibodies. Therefore, we aimed t...

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Detalles Bibliográficos
Autores: Rodriguez-Martinez, Lorena, García-Moreno, Cristina, Perez-Pampin, Eva, Gómara Elena, María José, Sarmiento-Monroy, Juan C., Lopez-Golán, Yolanda, Gómez-Puerta, José A., Mera-Varela, Antonio, Conde, Carmen, Sanmartí, Raimon, Haro Villar, Isabel, González, Antonio
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2023
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/337414
Acceso en línea:http://hdl.handle.net/10261/337414
https://api.elsevier.com/content/abstract/scopus_id/85173315513
Access Level:acceso abierto
Palabra clave:Rheumatoid arthritis
Autoantibodies
Biomarker
Heterogeneity
Meta-analysis
Post-translational modifications
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Descripción
Sumario:Autoantibodies are critical elements in RA pathogenesis and clinical assessment. The anti-malondialdehyde-acetaldehyde (anti-MAA) antibodies are potentially useful because of their claimed high sensitivity for all RA patients, including those lacking RF and anti-CCP antibodies. Therefore, we aimed to replicate these findings.

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