The role of gut microbiota in cerebrovascular disease and related dementia

In recent years, increasing evidence suggests that commensal microbiota may play an important role not only in health but also in disease including cerebrovascular disease. Gut microbes impact physiology, at least in part, by metabolizing dietary factors and host-derived substrates and then generati...

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Autores: Cuartero Desviat, María Isabel, García Culebras, Alicia, Nieto Vaquero, Carmen, Fraga, Enrique, Torres López, Cristina, Pradillo Justo, Jesús Miguel, Lizasoaín Hernández, Ignacio, Moro Sánchez, María Ángeles
Tipo de recurso: artículo
Fecha de publicación:2023
País:España
Institución:Universidad Complutense de Madrid (UCM)
Repositorio:Docta Complutense
Idioma:inglés
OAI Identifier:oai:docta.ucm.es:20.500.14352/103324
Acceso en línea:https://hdl.handle.net/20.500.14352/103324
Access Level:acceso abierto
Palabra clave:616.831-005
Dementia
Gut
Microbiota
Post-stroke cognitive impairment
Stroke
Neurociencias (Medicina)
3205.07 Neurología
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oai_identifier_str oai:docta.ucm.es:20.500.14352/103324
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network_name_str España
repository_id_str
spelling The role of gut microbiota in cerebrovascular disease and related dementiaCuartero Desviat, María IsabelGarcía Culebras, AliciaNieto Vaquero, CarmenFraga, EnriqueTorres López, CristinaPradillo Justo, Jesús MiguelLizasoaín Hernández, IgnacioMoro Sánchez, María Ángeles616.831-005DementiaGutMicrobiotaPost-stroke cognitive impairmentStrokeNeurociencias (Medicina)3205.07 NeurologíaIn recent years, increasing evidence suggests that commensal microbiota may play an important role not only in health but also in disease including cerebrovascular disease. Gut microbes impact physiology, at least in part, by metabolizing dietary factors and host-derived substrates and then generating active compounds including toxins. The purpose of this current review is to highlight the complex interplay between microbiota, their metabolites. and essential functions for human health, ranging from regulation of the metabolism and the immune system to modulation of brain development and function. We discuss the role of gut dysbiosis in cerebrovascular disease, specifically in acute and chronic stroke phases, and the possible implication of intestinal microbiota in post-stroke cognitive impairment and dementia, and we identify potential therapeutic opportunities of targeting microbiota in this context.WileyUniversidad Complutense de Madrid20232023-07-1220232023-07-12journal articlehttp://purl.org/coar/resource_type/c_6501VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/20.500.14352/103324reponame:Docta Complutenseinstname:Universidad Complutense de Madrid (UCM)Inglésengopen accesshttp://purl.org/coar/access_right/c_abf2Attribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:docta.ucm.es:20.500.14352/1033242026-06-02T12:44:21Z
dc.title.none.fl_str_mv The role of gut microbiota in cerebrovascular disease and related dementia
title The role of gut microbiota in cerebrovascular disease and related dementia
spellingShingle The role of gut microbiota in cerebrovascular disease and related dementia
Cuartero Desviat, María Isabel
616.831-005
Dementia
Gut
Microbiota
Post-stroke cognitive impairment
Stroke
Neurociencias (Medicina)
3205.07 Neurología
title_short The role of gut microbiota in cerebrovascular disease and related dementia
title_full The role of gut microbiota in cerebrovascular disease and related dementia
title_fullStr The role of gut microbiota in cerebrovascular disease and related dementia
title_full_unstemmed The role of gut microbiota in cerebrovascular disease and related dementia
title_sort The role of gut microbiota in cerebrovascular disease and related dementia
dc.creator.none.fl_str_mv Cuartero Desviat, María Isabel
García Culebras, Alicia
Nieto Vaquero, Carmen
Fraga, Enrique
Torres López, Cristina
Pradillo Justo, Jesús Miguel
Lizasoaín Hernández, Ignacio
Moro Sánchez, María Ángeles
author Cuartero Desviat, María Isabel
author_facet Cuartero Desviat, María Isabel
García Culebras, Alicia
Nieto Vaquero, Carmen
Fraga, Enrique
Torres López, Cristina
Pradillo Justo, Jesús Miguel
Lizasoaín Hernández, Ignacio
Moro Sánchez, María Ángeles
author_role author
author2 García Culebras, Alicia
Nieto Vaquero, Carmen
Fraga, Enrique
Torres López, Cristina
Pradillo Justo, Jesús Miguel
Lizasoaín Hernández, Ignacio
Moro Sánchez, María Ángeles
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidad Complutense de Madrid
dc.subject.none.fl_str_mv 616.831-005
Dementia
Gut
Microbiota
Post-stroke cognitive impairment
Stroke
Neurociencias (Medicina)
3205.07 Neurología
topic 616.831-005
Dementia
Gut
Microbiota
Post-stroke cognitive impairment
Stroke
Neurociencias (Medicina)
3205.07 Neurología
description In recent years, increasing evidence suggests that commensal microbiota may play an important role not only in health but also in disease including cerebrovascular disease. Gut microbes impact physiology, at least in part, by metabolizing dietary factors and host-derived substrates and then generating active compounds including toxins. The purpose of this current review is to highlight the complex interplay between microbiota, their metabolites. and essential functions for human health, ranging from regulation of the metabolism and the immune system to modulation of brain development and function. We discuss the role of gut dysbiosis in cerebrovascular disease, specifically in acute and chronic stroke phases, and the possible implication of intestinal microbiota in post-stroke cognitive impairment and dementia, and we identify potential therapeutic opportunities of targeting microbiota in this context.
publishDate 2023
dc.date.none.fl_str_mv 2023
2023-07-12
2023
2023-07-12
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
VoR
http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://hdl.handle.net/20.500.14352/103324
url https://hdl.handle.net/20.500.14352/103324
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution 4.0 International
http://creativecommons.org/licenses/by/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution 4.0 International
http://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Wiley
publisher.none.fl_str_mv Wiley
dc.source.none.fl_str_mv reponame:Docta Complutense
instname:Universidad Complutense de Madrid (UCM)
instname_str Universidad Complutense de Madrid (UCM)
reponame_str Docta Complutense
collection Docta Complutense
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15.301603

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