Generation of a porous scaffold with a starting composition in the CaO-SiO2-MgO-P2O5 system in a simulated physiological environment

Magnesium-based ceramics are involved in orthopedic applications such as bone scaffolds or implant coatings. They provide structural support to cells for bone ingrowth, but highly porous matrices cannot resist severe mechanical stress during implantation. In this study, the laser floating zone (LFZ)...

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Autores: Grima, L., Díaz-Pérez, M., Gil, J., Sola, D., Peña, J. I.
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2020
País:España
Institución:Universidad de Zaragoza
Repositorio:Zaguán. Repositorio Digital de la Universidad de Zaragoza
OAI Identifier:oai:zaguan.unizar.es:95909
Acceso en línea:http://zaguan.unizar.es/record/95909
Access Level:acceso abierto
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spelling Generation of a porous scaffold with a starting composition in the CaO-SiO2-MgO-P2O5 system in a simulated physiological environmentGrima, L.Díaz-Pérez, M.Gil, J.Sola, D.Peña, J. I.Magnesium-based ceramics are involved in orthopedic applications such as bone scaffolds or implant coatings. They provide structural support to cells for bone ingrowth, but highly porous matrices cannot resist severe mechanical stress during implantation. In this study, the laser floating zone (LFZ) technique is used to prepare a dense crystalline material with composition in the CaO-SiO2-MgO-P2O5 system. This material, under physiological conditions, is able to generate a porous scaffold controlled by the dissolution of the MgO phase, meeting the mechanical advantages of a dense material and the biological features of a porous scaffold. FESEM (Field emission scanning electron microscopy), XRD (X-ray Diffraction), EDS (Energy Dispersive X-rays spectroscopy), and ICP ((Inductively Coupled Plasma) analysis were carried out in order to characterize the samples before and after immersion in simulated body fluid (SBF).2020info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://zaguan.unizar.es/record/95909reponame:Zaguán. Repositorio Digital de la Universidad de Zaragozainstname:Universidad de ZaragozaInglésinfo:eu-repo/grantAgreement/EC/H2020/795630This project has received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement No H2020 795630-LasInPOPinfo:eu-repo/semantics/openAccessoai:zaguan.unizar.es:959092026-05-29T13:59:51Z
dc.title.none.fl_str_mv Generation of a porous scaffold with a starting composition in the CaO-SiO2-MgO-P2O5 system in a simulated physiological environment
title Generation of a porous scaffold with a starting composition in the CaO-SiO2-MgO-P2O5 system in a simulated physiological environment
spellingShingle Generation of a porous scaffold with a starting composition in the CaO-SiO2-MgO-P2O5 system in a simulated physiological environment
Grima, L.
title_short Generation of a porous scaffold with a starting composition in the CaO-SiO2-MgO-P2O5 system in a simulated physiological environment
title_full Generation of a porous scaffold with a starting composition in the CaO-SiO2-MgO-P2O5 system in a simulated physiological environment
title_fullStr Generation of a porous scaffold with a starting composition in the CaO-SiO2-MgO-P2O5 system in a simulated physiological environment
title_full_unstemmed Generation of a porous scaffold with a starting composition in the CaO-SiO2-MgO-P2O5 system in a simulated physiological environment
title_sort Generation of a porous scaffold with a starting composition in the CaO-SiO2-MgO-P2O5 system in a simulated physiological environment
dc.creator.none.fl_str_mv Grima, L.
Díaz-Pérez, M.
Gil, J.
Sola, D.
Peña, J. I.
author Grima, L.
author_facet Grima, L.
Díaz-Pérez, M.
Gil, J.
Sola, D.
Peña, J. I.
author_role author
author2 Díaz-Pérez, M.
Gil, J.
Sola, D.
Peña, J. I.
author2_role author
author
author
author
description Magnesium-based ceramics are involved in orthopedic applications such as bone scaffolds or implant coatings. They provide structural support to cells for bone ingrowth, but highly porous matrices cannot resist severe mechanical stress during implantation. In this study, the laser floating zone (LFZ) technique is used to prepare a dense crystalline material with composition in the CaO-SiO2-MgO-P2O5 system. This material, under physiological conditions, is able to generate a porous scaffold controlled by the dissolution of the MgO phase, meeting the mechanical advantages of a dense material and the biological features of a porous scaffold. FESEM (Field emission scanning electron microscopy), XRD (X-ray Diffraction), EDS (Energy Dispersive X-rays spectroscopy), and ICP ((Inductively Coupled Plasma) analysis were carried out in order to characterize the samples before and after immersion in simulated body fluid (SBF).
publishDate 2020
dc.date.none.fl_str_mv 2020
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
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status_str publishedVersion
dc.identifier.none.fl_str_mv http://zaguan.unizar.es/record/95909
url http://zaguan.unizar.es/record/95909
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv info:eu-repo/grantAgreement/EC/H2020/795630
This project has received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement No H2020 795630-LasInPOP
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
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dc.source.none.fl_str_mv reponame:Zaguán. Repositorio Digital de la Universidad de Zaragoza
instname:Universidad de Zaragoza
instname_str Universidad de Zaragoza
reponame_str Zaguán. Repositorio Digital de la Universidad de Zaragoza
collection Zaguán. Repositorio Digital de la Universidad de Zaragoza
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