An overview of the applications of chiral phosphoric acid organocatalysts in enantioselective additions to C=O and C=N bonds

Chiral phosphoric acids (CPAs) have been used as efficient organocatalysts since the first examples were reported 18 years ago by Akiyama and Terada. Although they were originally developed for enantioselective additions to imines, a wide reaction scope has been demonstrated using this type of catal...

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Detalles Bibliográficos
Autores: Del Corte Solaguren-Beascoa, Xabier, Martínez de Marigorta Izaga, Edorta, Palacios Gambra, Francisco Javier, Vicario Hernando, Javier, Maestro Burzaco, Aitor
Tipo de recurso: artículo
Fecha de publicación:2022
País:España
Institución:Universidad del País Vasco
Repositorio:Addi. Archivo Digital para la Docencia y la Investigación
OAI Identifier:oai:addi.ehu.eus:10810/70065
Acceso en línea:http://hdl.handle.net/10810/70065
Access Level:acceso abierto
Palabra clave:chiral phosphoric acids
nucleophilic addition
imines
carbonyl compounds
asymmetric organocatalysis
Descripción
Sumario:Chiral phosphoric acids (CPAs) have been used as efficient organocatalysts since the first examples were reported 18 years ago by Akiyama and Terada. Although they were originally developed for enantioselective additions to imines, a wide reaction scope has been demonstrated using this type of catalyst. In this review, the known applications of CPA for enantioselective additions to C=O and C=N bonds are covered.