3-Pyrazolines (2,3-dihydro-1H-pyrazoles): Synthesis, reactivity, and physical and biological properties

This account provides a summary of the current knowledge on 3-pyrazolines, an important but rather neglected field of heterocyclic chemistry. The review is divided into sections on the synthesis, reactivity, structure and biological properties and covers the literature from 1937 to 2020. In an effor...

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Detalhes bibliográficos
Autores: Hoz, Antonio de la, Claramunt, Rosa M., Elguero, José, Alkorta, Ibon
Tipo de documento: artigo
Estado:Versão publicada
Data de publicação:2021
País:España
Recursos:Consejo Superior de Investigaciones Científicas (CSIC)
Repositório:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/255009
Acesso em linha:http://hdl.handle.net/10261/255009
Access Level:Acceso aberto
Palavra-chave:Pyrazolines
Dihydropyrazoles
Tautomerism
Protonation
NMR
X-ray structures
Descrição
Resumo:This account provides a summary of the current knowledge on 3-pyrazolines, an important but rather neglected field of heterocyclic chemistry. The review is divided into sections on the synthesis, reactivity, structure and biological properties and covers the literature from 1937 to 2020. In an effort to clarify some results, theoretical calculations were carried out anew.