Diagnosis and Treatment of Renal ANCA Vasculitis

The document provides a comprehensive overview of the diagnosis, monitoring, and treatment of anti-neutrophil cytoplasmic antibody-associated vasculitis (AAV) with renal involvement, focusing on granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA). It outlines the definitions, c...

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Detalhes bibliográficos
Autores: Bordignon Draibe, Juliana, Marco Rusiñol, Helena|||0000-0002-7229-8729, Ibernon, Meritxell, Agraz Pamplona, Irene|||0000-0002-4223-6834, Arcal, Carola, Barros, Xoana|||0000-0001-9690-9769, Cabrera, Victoria, Da Silva, Iara, Díaz Encarnación, Montserrat Mercedes|||0000-0001-5172-3370, Fulladosa, Xavier|||0000-0003-1974-9874, Guillén Gómez, Elena|||0000-0002-8498-2579, Lescano, Patricia, Martínez Valenzuela, Laura|||0000-0003-1230-3423, Márquez, Eva, Martín Alemany, Nàdia|||0000-0002-4370-7562, Merino Ribas, Ana|||0000-0002-8322-4047, Navarro Diaz, Maruja Isabel|||0000-0003-3001-0595, Rodríguez García, Eva, Soler, María José|||0000-0003-3621-0766, Torras, Joan|||0000-0002-1135-7588, Quintana, Luis F.|||0000-0001-7582-8476
Formato: artículo
Fecha de publicación:2024
País:España
Recursos:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:ddd.uab.cat:309317
Acesso em linha:https://ddd.uab.cat/record/309317
https://dx.doi.org/urn:doi:10.3390/jcm13226793
Access Level:acceso abierto
Palavra-chave:Anti-neutrophil cytoplasmic antibody-associated vasculitis
Eosinophilic granulomatosis with polyangiitis
Granulomatosis with polyangiitis
Microscopic polyangiitis
Descrição
Resumo:The document provides a comprehensive overview of the diagnosis, monitoring, and treatment of anti-neutrophil cytoplasmic antibody-associated vasculitis (AAV) with renal involvement, focusing on granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA). It outlines the definitions, clinical presentation, histopathological classification, monitoring strategies, induction and maintenance treatments, as well as special considerations for relapsing, refractory, and frail patients with renal AAV. The document was prepared by the Catalan Group for the Study of Glomerular Diseases (GLOMCAT), which comprises nephrologists with extensive experience in the diagnosis and treatment of AAV patients. Several virtual and face-to-face meetings were held for coordination, section assignments, and content discussion. An exhaustive and systematic search of the literature was carried out, which included, among others, the following databases: PubMed, EMBASE, Cochrane Library, Google Scholar, and ClinicalTrials.gov, as well as the abstract books of national and international congresses. Overall, the document provides a comprehensive guide for clinicians managing patients with renal AAV, offering evidence-based recommendations for diagnosis, monitoring, and treatment across various clinical scenarios.

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