Clinical and prognostic differences between methicillin-resistant and methicillin-susceptible Staphylococcus aureus infective endocarditis

[Background] S. aureus (SA) infective endocarditis (IE) has a very high mortality, attributed to the age and comorbidities of patients, inadequate or delayed antibiotic treatment, and methicillin resistance, among other causes. The main study objective was to analyze epidemiological and clinical dif...

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Detalhes bibliográficos
Autores: Hidalgo-Tenorio, Carmen, Gálvez-Acebal, Juan, Martínez-Marcos, Francisco Javier, Plata-Ciezar, Antonio, Torre, Javier de la, López-Cortés, Luis Eduardo, Noureddine, Mariam, Reguera Iglesias, José María, Vinuesa García, David, García-López, María Victoria, Ojeda Burgos, Guillermo, Luque-Márquez, Rafael, Lomas-Cabezas, José Manuel, Lepe, José A., Alarcón González, Arístides de
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2020
País:España
Recursos:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/236486
Acesso em linha:http://hdl.handle.net/10261/236486
Access Level:acceso abierto
Palavra-chave:Endocarditis
Staphylococcus aureus
Vancomycin
Methicillin resistance
Descrição
Resumo:[Background] S. aureus (SA) infective endocarditis (IE) has a very high mortality, attributed to the age and comorbidities of patients, inadequate or delayed antibiotic treatment, and methicillin resistance, among other causes. The main study objective was to analyze epidemiological and clinical differences between IE by methicillin-resistant versus methicillin-susceptible SA (MRSA vs. MSSA) and to examine prognostic factors for SA endocarditis, including methicillin resistance and vancomycin minimum inhibitory concentration (MIC) values > 1 μg/mL to MRSA.

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