A New Pre-descemetic Corneal Ring (Neoring) in Deep Anterior Lamellar Keratoplasty for Moderate-Advanced Keratoconus: A Pilot 2-Year Long-Term Follow-Up Study

Purpose: To assess the outcomes of implanting a new polymethylmethacrylate (PMMA) ring (Neoring; AJL Ophthalmic) in pre-descemet deep anterior lamellar keratoplasty (PD-DALK) procedure for moderate-advanced keratoconus. Methods: This prospective study included 10 eyes of 10 patients with moderate-ad...

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Autores: Alfonso Bartolozzi, Belén, Lisa Fernández, Carlos, Fernández-Vega Cueto, Luis, Madrid Costa, David, Alfonso Sánchez, José F.
Tipo de recurso: artículo
Fecha de publicación:2021
País:España
Institución:Universidad Complutense de Madrid (UCM)
Repositorio:Docta Complutense
Idioma:inglés
OAI Identifier:oai:docta.ucm.es:20.500.14352/4578
Acceso en línea:https://hdl.handle.net/20.500.14352/4578
Access Level:acceso abierto
Palabra clave:617.713-007.64-089
615.46:617.713
681.735
Corneal transplant
Deep anterior lamellar keratoplasty (DALK)
Visual outcomes
Refractive outcomes
Keratoconus
Cirugía
Oftalmología
Materiales ópticos
3213 Cirugía
3201.09 Oftalmología
2209.14 Propiedad ópticas de los sólidos
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oai_identifier_str oai:docta.ucm.es:20.500.14352/4578
network_acronym_str ES
network_name_str España
repository_id_str
spelling A New Pre-descemetic Corneal Ring (Neoring) in Deep Anterior Lamellar Keratoplasty for Moderate-Advanced Keratoconus: A Pilot 2-Year Long-Term Follow-Up StudyAlfonso Bartolozzi, BelénLisa Fernández, CarlosFernández-Vega Cueto, LuisMadrid Costa, DavidAlfonso Sánchez, José F.617.713-007.64-089615.46:617.713681.735Corneal transplantDeep anterior lamellar keratoplasty (DALK)Visual outcomesRefractive outcomesKeratoconusCirugíaOftalmologíaMateriales ópticos3213 Cirugía3201.09 Oftalmología2209.14 Propiedad ópticas de los sólidosPurpose: To assess the outcomes of implanting a new polymethylmethacrylate (PMMA) ring (Neoring; AJL Ophthalmic) in pre-descemet deep anterior lamellar keratoplasty (PD-DALK) procedure for moderate-advanced keratoconus. Methods: This prospective study included 10 eyes of 10 patients with moderate-advanced keratoconus who underwent PD-DALK with Neoring implantation. Neoring was implanted in a pre-descemetic pocket. The post-operative examination included refraction, corrected distance visual acuity (CDVA), corneal tomography, and endothelial cell density (ECD). The root mean squares (RMSs) for coma-like aberrations and spherical aberration were evaluated for a pupil size of 4.5mm. The junctional graft (Tg) and host (Th) thicknesses were measured. The post-operative follow-up was 24 months. Results: Post-operative CDVA was 0.82 ± 0.14 (decimal scale), 100% of the eyes achieved a CDVA of 0.7 (decimal scale). The refractive cylinder was −2.86 ± 1.65 2-years after surgery. No eyes had a post-operative refractive cylinder ≥5.00 D and in five eyes (50%), it was ≤2.50 D. At the last visit, the mean keratometry was 45.64 ± 1.96 D, the RMS for coma-like aberrations was 0.30 ± 0.15μm and spherical aberration was 0.22 ± 0.09. The mean ECD remains without changes over the follow-up (P = 0.07). At the last visit, Tg and Th were 679.9 ± 39.0 and 634.8 ± 41.2μm, respectively. The thickness of the complex (host-Neoring) was 740.6 ± 35.6μm. In all cases, this thickness was thicker than Tg. Conclusion: The results of this study suggest that PD-DALK along Neoring implantation is a viable, effective, and safe option to optimize the post-operative results for moderate-severe keratoconusFrontiers MediaUniversidad Complutense de Madrid20212021-11-0420212021-11-04journal articlehttp://purl.org/coar/resource_type/c_6501info:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/20.500.14352/4578reponame:Docta Complutenseinstname:Universidad Complutense de Madrid (UCM)Inglésengopen accesshttp://purl.org/coar/access_right/c_abf2Atribución 3.0 Españahttps://creativecommons.org/licenses/by/3.0/es/info:eu-repo/semantics/openAccessoai:docta.ucm.es:20.500.14352/45782026-06-02T12:44:21Z
dc.title.none.fl_str_mv A New Pre-descemetic Corneal Ring (Neoring) in Deep Anterior Lamellar Keratoplasty for Moderate-Advanced Keratoconus: A Pilot 2-Year Long-Term Follow-Up Study
title A New Pre-descemetic Corneal Ring (Neoring) in Deep Anterior Lamellar Keratoplasty for Moderate-Advanced Keratoconus: A Pilot 2-Year Long-Term Follow-Up Study
spellingShingle A New Pre-descemetic Corneal Ring (Neoring) in Deep Anterior Lamellar Keratoplasty for Moderate-Advanced Keratoconus: A Pilot 2-Year Long-Term Follow-Up Study
Alfonso Bartolozzi, Belén
617.713-007.64-089
615.46:617.713
681.735
Corneal transplant
Deep anterior lamellar keratoplasty (DALK)
Visual outcomes
Refractive outcomes
Keratoconus
Cirugía
Oftalmología
Materiales ópticos
3213 Cirugía
3201.09 Oftalmología
2209.14 Propiedad ópticas de los sólidos
title_short A New Pre-descemetic Corneal Ring (Neoring) in Deep Anterior Lamellar Keratoplasty for Moderate-Advanced Keratoconus: A Pilot 2-Year Long-Term Follow-Up Study
title_full A New Pre-descemetic Corneal Ring (Neoring) in Deep Anterior Lamellar Keratoplasty for Moderate-Advanced Keratoconus: A Pilot 2-Year Long-Term Follow-Up Study
title_fullStr A New Pre-descemetic Corneal Ring (Neoring) in Deep Anterior Lamellar Keratoplasty for Moderate-Advanced Keratoconus: A Pilot 2-Year Long-Term Follow-Up Study
title_full_unstemmed A New Pre-descemetic Corneal Ring (Neoring) in Deep Anterior Lamellar Keratoplasty for Moderate-Advanced Keratoconus: A Pilot 2-Year Long-Term Follow-Up Study
title_sort A New Pre-descemetic Corneal Ring (Neoring) in Deep Anterior Lamellar Keratoplasty for Moderate-Advanced Keratoconus: A Pilot 2-Year Long-Term Follow-Up Study
dc.creator.none.fl_str_mv Alfonso Bartolozzi, Belén
Lisa Fernández, Carlos
Fernández-Vega Cueto, Luis
Madrid Costa, David
Alfonso Sánchez, José F.
author Alfonso Bartolozzi, Belén
author_facet Alfonso Bartolozzi, Belén
Lisa Fernández, Carlos
Fernández-Vega Cueto, Luis
Madrid Costa, David
Alfonso Sánchez, José F.
author_role author
author2 Lisa Fernández, Carlos
Fernández-Vega Cueto, Luis
Madrid Costa, David
Alfonso Sánchez, José F.
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Universidad Complutense de Madrid
dc.subject.none.fl_str_mv 617.713-007.64-089
615.46:617.713
681.735
Corneal transplant
Deep anterior lamellar keratoplasty (DALK)
Visual outcomes
Refractive outcomes
Keratoconus
Cirugía
Oftalmología
Materiales ópticos
3213 Cirugía
3201.09 Oftalmología
2209.14 Propiedad ópticas de los sólidos
topic 617.713-007.64-089
615.46:617.713
681.735
Corneal transplant
Deep anterior lamellar keratoplasty (DALK)
Visual outcomes
Refractive outcomes
Keratoconus
Cirugía
Oftalmología
Materiales ópticos
3213 Cirugía
3201.09 Oftalmología
2209.14 Propiedad ópticas de los sólidos
description Purpose: To assess the outcomes of implanting a new polymethylmethacrylate (PMMA) ring (Neoring; AJL Ophthalmic) in pre-descemet deep anterior lamellar keratoplasty (PD-DALK) procedure for moderate-advanced keratoconus. Methods: This prospective study included 10 eyes of 10 patients with moderate-advanced keratoconus who underwent PD-DALK with Neoring implantation. Neoring was implanted in a pre-descemetic pocket. The post-operative examination included refraction, corrected distance visual acuity (CDVA), corneal tomography, and endothelial cell density (ECD). The root mean squares (RMSs) for coma-like aberrations and spherical aberration were evaluated for a pupil size of 4.5mm. The junctional graft (Tg) and host (Th) thicknesses were measured. The post-operative follow-up was 24 months. Results: Post-operative CDVA was 0.82 ± 0.14 (decimal scale), 100% of the eyes achieved a CDVA of 0.7 (decimal scale). The refractive cylinder was −2.86 ± 1.65 2-years after surgery. No eyes had a post-operative refractive cylinder ≥5.00 D and in five eyes (50%), it was ≤2.50 D. At the last visit, the mean keratometry was 45.64 ± 1.96 D, the RMS for coma-like aberrations was 0.30 ± 0.15μm and spherical aberration was 0.22 ± 0.09. The mean ECD remains without changes over the follow-up (P = 0.07). At the last visit, Tg and Th were 679.9 ± 39.0 and 634.8 ± 41.2μm, respectively. The thickness of the complex (host-Neoring) was 740.6 ± 35.6μm. In all cases, this thickness was thicker than Tg. Conclusion: The results of this study suggest that PD-DALK along Neoring implantation is a viable, effective, and safe option to optimize the post-operative results for moderate-severe keratoconus
publishDate 2021
dc.date.none.fl_str_mv 2021
2021-11-04
2021
2021-11-04
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://hdl.handle.net/20.500.14352/4578
url https://hdl.handle.net/20.500.14352/4578
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Atribución 3.0 España
https://creativecommons.org/licenses/by/3.0/es/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Atribución 3.0 España
https://creativecommons.org/licenses/by/3.0/es/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Frontiers Media
publisher.none.fl_str_mv Frontiers Media
dc.source.none.fl_str_mv reponame:Docta Complutense
instname:Universidad Complutense de Madrid (UCM)
instname_str Universidad Complutense de Madrid (UCM)
reponame_str Docta Complutense
collection Docta Complutense
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15.300724

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