Stage-specific transcriptomic analysis reveals insights into the development, reproduction and biological function of allergens in the European house dust mite Dermatophagoides pteronyssinus

House dust mites (HDMs) such as Dermatophagoides pteronyssinus are major allergy elicitors worldwide, yet their gene expression across developmental stages remains underexplored. Herein, we report a comprehensive RNAseq analysis of larvae, nymphs, and adult males and females, mapped to a recently pu...

ver descrição completa

Detalhes bibliográficos
Autores: Vidal Quist, José Cristian, Ortego, Félix, Lambrecht, Bart N., Rombauts, Stephane, Hernández-Crespo, Pedro
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2025
País:España
Recursos:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/416277
Acesso em linha:http://hdl.handle.net/10261/416277
https://api.elsevier.com/content/abstract/scopus_id/105006434417
Access Level:acceso abierto
Palavra-chave:Dermatophagoides pteronyssinus
Allergen
Cuticular protein
Development
Ecdysteroid
Horizontal gene transfer
House dust mite
RNAseq
Reproduction
Seminal fluid protein
id ES_6f6da09eb9a2dc2d9eaf2b2ecaa1378a
oai_identifier_str oai:digital.csic.es:10261/416277
network_acronym_str ES
network_name_str España
repository_id_str
spelling Stage-specific transcriptomic analysis reveals insights into the development, reproduction and biological function of allergens in the European house dust mite Dermatophagoides pteronyssinusVidal Quist, José CristianOrtego, FélixLambrecht, Bart N.Rombauts, StephaneHernández-Crespo, PedroDermatophagoides pteronyssinusAllergenCuticular proteinDevelopmentEcdysteroidHorizontal gene transferHouse dust miteRNAseqReproductionSeminal fluid proteinHouse dust mites (HDMs) such as Dermatophagoides pteronyssinus are major allergy elicitors worldwide, yet their gene expression across developmental stages remains underexplored. Herein, we report a comprehensive RNAseq analysis of larvae, nymphs, and adult males and females, mapped to a recently published high-quality genome with extended functional annotations.BNL's work is funded by a Fonds Wetenschappelijk Onderzoek (FWO) Methusalem grant (Nr. 01M01521).Peer reviewedSpringer NatureStichting ter Bevordering van Natuurwetenschappelijk Onderzoek (The Netherlands)Hernández-Crespo, Pedro [0000-0001-9350-3640]Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]202620262025info:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_6501Publisher's versioninfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://hdl.handle.net/10261/416277https://api.elsevier.com/content/abstract/scopus_id/105006434417reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)Ingléshttps://doi.org/10.1186/s12864-025-11703-wSíinfo:eu-repo/semantics/openAccessoai:digital.csic.es:10261/4162772026-05-22T06:33:51Z
dc.title.none.fl_str_mv Stage-specific transcriptomic analysis reveals insights into the development, reproduction and biological function of allergens in the European house dust mite Dermatophagoides pteronyssinus
title Stage-specific transcriptomic analysis reveals insights into the development, reproduction and biological function of allergens in the European house dust mite Dermatophagoides pteronyssinus
spellingShingle Stage-specific transcriptomic analysis reveals insights into the development, reproduction and biological function of allergens in the European house dust mite Dermatophagoides pteronyssinus
Vidal Quist, José Cristian
Dermatophagoides pteronyssinus
Allergen
Cuticular protein
Development
Ecdysteroid
Horizontal gene transfer
House dust mite
RNAseq
Reproduction
Seminal fluid protein
title_short Stage-specific transcriptomic analysis reveals insights into the development, reproduction and biological function of allergens in the European house dust mite Dermatophagoides pteronyssinus
title_full Stage-specific transcriptomic analysis reveals insights into the development, reproduction and biological function of allergens in the European house dust mite Dermatophagoides pteronyssinus
title_fullStr Stage-specific transcriptomic analysis reveals insights into the development, reproduction and biological function of allergens in the European house dust mite Dermatophagoides pteronyssinus
title_full_unstemmed Stage-specific transcriptomic analysis reveals insights into the development, reproduction and biological function of allergens in the European house dust mite Dermatophagoides pteronyssinus
title_sort Stage-specific transcriptomic analysis reveals insights into the development, reproduction and biological function of allergens in the European house dust mite Dermatophagoides pteronyssinus
dc.creator.none.fl_str_mv Vidal Quist, José Cristian
Ortego, Félix
Lambrecht, Bart N.
Rombauts, Stephane
Hernández-Crespo, Pedro
author Vidal Quist, José Cristian
author_facet Vidal Quist, José Cristian
Ortego, Félix
Lambrecht, Bart N.
Rombauts, Stephane
Hernández-Crespo, Pedro
author_role author
author2 Ortego, Félix
Lambrecht, Bart N.
Rombauts, Stephane
Hernández-Crespo, Pedro
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Stichting ter Bevordering van Natuurwetenschappelijk Onderzoek (The Netherlands)
Hernández-Crespo, Pedro [0000-0001-9350-3640]
Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]
dc.subject.none.fl_str_mv Dermatophagoides pteronyssinus
Allergen
Cuticular protein
Development
Ecdysteroid
Horizontal gene transfer
House dust mite
RNAseq
Reproduction
Seminal fluid protein
topic Dermatophagoides pteronyssinus
Allergen
Cuticular protein
Development
Ecdysteroid
Horizontal gene transfer
House dust mite
RNAseq
Reproduction
Seminal fluid protein
description House dust mites (HDMs) such as Dermatophagoides pteronyssinus are major allergy elicitors worldwide, yet their gene expression across developmental stages remains underexplored. Herein, we report a comprehensive RNAseq analysis of larvae, nymphs, and adult males and females, mapped to a recently published high-quality genome with extended functional annotations.
publishDate 2025
dc.date.none.fl_str_mv 2025
2026
2026
dc.type.none.fl_str_mv info:eu-repo/semantics/article
http://purl.org/coar/resource_type/c_6501
Publisher's version
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10261/416277
https://api.elsevier.com/content/abstract/scopus_id/105006434417
url http://hdl.handle.net/10261/416277
https://api.elsevier.com/content/abstract/scopus_id/105006434417
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv https://doi.org/10.1186/s12864-025-11703-w
Sí
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Springer Nature
publisher.none.fl_str_mv Springer Nature
dc.source.none.fl_str_mv reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC
instname:Consejo Superior de Investigaciones Científicas (CSIC)
instname_str Consejo Superior de Investigaciones Científicas (CSIC)
reponame_str DIGITAL.CSIC. Repositorio Institucional del CSIC
collection DIGITAL.CSIC. Repositorio Institucional del CSIC
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869410495223562240
score 15,811543

Registos relacionados