Stage-specific transcriptomic analysis reveals insights into the development, reproduction and biological function of allergens in the European house dust mite Dermatophagoides pteronyssinus

House dust mites (HDMs) such as Dermatophagoides pteronyssinus are major allergy elicitors worldwide, yet their gene expression across developmental stages remains underexplored. Herein, we report a comprehensive RNAseq analysis of larvae, nymphs, and adult males and females, mapped to a recently pu...

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Detalles Bibliográficos
Autores: Vidal Quist, José Cristian, Ortego, Félix, Lambrecht, Bart N., Rombauts, Stephane, Hernández-Crespo, Pedro
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2025
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/416277
Acceso en línea:http://hdl.handle.net/10261/416277
https://api.elsevier.com/content/abstract/scopus_id/105006434417
Access Level:acceso abierto
Palabra clave:Dermatophagoides pteronyssinus
Allergen
Cuticular protein
Development
Ecdysteroid
Horizontal gene transfer
House dust mite
RNAseq
Reproduction
Seminal fluid protein
Descripción
Sumario:House dust mites (HDMs) such as Dermatophagoides pteronyssinus are major allergy elicitors worldwide, yet their gene expression across developmental stages remains underexplored. Herein, we report a comprehensive RNAseq analysis of larvae, nymphs, and adult males and females, mapped to a recently published high-quality genome with extended functional annotations.