Whither magnetic hyperthermia? A tentative roadmap

The scientific community has made great efforts in advancing magnetic hyperthermia for the last two decades after going through a sizeable research lapse from its establishment. All the progress made in various topics ranging from nanoparticle synthesis to biocompatibilization and in vivo testing ha...

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Detalles Bibliográficos
Autores: Rubia Rodríguez, Irene, Santana Otero, Antonio, Spassov, Simo, Tombácz, Etelka, Johansson, Christer, Presa Muñoz De Toro, Patricia Marcela De La, Teran, Francisco J., Puerto Morales, María del, Veintemillas Verdaguer, Sabino, Thanh, Nguyen T. K, Ortega, Daniel
Tipo de recurso: artículo
Fecha de publicación:2021
País:España
Institución:Universidad Complutense de Madrid (UCM)
Repositorio:Docta Complutense
Idioma:inglés
OAI Identifier:oai:docta.ucm.es:20.500.14352/7417
Acceso en línea:https://hdl.handle.net/20.500.14352/7417
Access Level:acceso abierto
Palabra clave:538.9
Magnetic hyperthermia
Magnetic nanoparticles
Hysteresis losses
Cancer
Magnetic particle imaging
Theranostics
Nanoparticles synthesis
Thermometry
Standardization
Nanotoxicity
Física de materiales
Física del estado sólido
2211 Física del Estado Sólido
Descripción
Sumario:The scientific community has made great efforts in advancing magnetic hyperthermia for the last two decades after going through a sizeable research lapse from its establishment. All the progress made in various topics ranging from nanoparticle synthesis to biocompatibilization and in vivo testing have been seeking to push the forefront towards some new clinical trials. As many, they did not go at the expected pace. Today, fruitful international cooperation and the wisdom gain after a careful analysis of the lessons learned from seminal clinical trials allow us to have a future with better guarantees for a more definitive takeoff of this genuine nanotherapy against cancer. Deliberately giving prominence to a number of critical aspects, this opinion review offers a blend of state-of-the-art hints and glimpses into the future of the therapy, considering the expected evolution of science and technology behind magnetic hyperthermia.