Antifouling coatings for dental implants: Polyethylene glycol-like coatings on titanium by plasma polymerization
Titanium dental implants are commonly used for the replacement of lost teeth, but they present a considerable number of failures due to the infection on surrounding tissues. The aim of this paper is the development of a polyethylene glycol-like (PEG-like) coating on the titanium surface by plasma po...
| Autores: | , , , , , |
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| Tipo de recurso: | artículo |
| Fecha de publicación: | 2015 |
| País: | España |
| Institución: | Universitat Politècnica de Catalunya (UPC) |
| Repositorio: | UPCommons. Portal del coneixement obert de la UPC |
| Idioma: | inglés |
| OAI Identifier: | oai:upcommons.upc.edu:2117/86626 |
| Acceso en línea: | https://hdl.handle.net/2117/86626 https://dx.doi.org/10.1116/1.4913376 |
| Access Level: | acceso abierto |
| Palabra clave: | Titanium Dental implants dielectric barrier discharges bacterial adhesion antibacterial activity poly(ethylene glycol) protein adsorption covalent immobilization peri-implantitis surface-analysis ethylene-oxide low-pressure Titani Implants dentals Àrees temàtiques de la UPC::Enginyeria dels materials |
| Sumario: | Titanium dental implants are commonly used for the replacement of lost teeth, but they present a considerable number of failures due to the infection on surrounding tissues. The aim of this paper is the development of a polyethylene glycol-like (PEG-like) coating on the titanium surface by plasma polymerization to obtain a novel improved surface with suitable low bacterial adhesion and adequate cell response. Surface analysis data of these coatings are presented, in particular, water contact angle, surface roughness, and film chemistry, demonstrating the presence of a PEG-like coating. Streptococcus sanguinis and Lactobacillus salivarius bacterial adhesion assays showed a decreased adhesion on the plasma polymerized samples, while cell adhesion of fibroblasts and osteoblasts on the treated surfaces was similar to control surfaces. Thus, the PEG-like antifouling coating obtained by plasma polymerization on Ti confers this biomaterial's highly suitable properties for dental applications, as they reduce the possibility of infection while allowing the tissue integration around the implant. (C) 2015 American Vacuum Society. |
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