Biofunctional polyethylene glycol coatings on titanium: an in vitro-based comparison of functionalization methods

Three methods for the production of Polyethylene glycol (PEG) coatings on titanium are compared, i.e. plasma polymerization, electrodeposition and silanization. The compared deposition methods presented similar wettability (hydrophilic coatings), chemical composition assessed by XPS and thickness ar...

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Detalles Bibliográficos
Autores: Buxadera Palomero, Judit|||0000-0003-0897-2093, Calvo Muñoz, Cristina, Torrent Camarero, Sergi|||0000-0002-1399-066X, Gil Mur, Francisco Javier|||0000-0002-6824-1412, Mas Moruno, Carlos|||0000-0001-8337-0872, Canal Barnils, Cristina|||0000-0002-3039-7462, Rodríguez Rius, Daniel|||0000-0001-6286-5200
Tipo de recurso: artículo
Fecha de publicación:2017
País:España
Institución:Universitat Politècnica de Catalunya (UPC)
Repositorio:UPCommons. Portal del coneixement obert de la UPC
Idioma:inglés
OAI Identifier:oai:upcommons.upc.edu:2117/102488
Acceso en línea:https://hdl.handle.net/2117/102488
https://dx.doi.org/10.1016/j.colsurfb.2017.01.042
Access Level:acceso abierto
Palabra clave:Coatings
Titanium
Dental implants
Polyethylene glycol
Titanium implants
Biofunctionalization
Plasma Polymerization
Silanization
Electrodeposition
Revestiments
Titani
Implants dentals
Àrees temàtiques de la UPC::Enginyeria dels materials
Descripción
Sumario:Three methods for the production of Polyethylene glycol (PEG) coatings on titanium are compared, i.e. plasma polymerization, electrodeposition and silanization. The compared deposition methods presented similar wettability (hydrophilic coatings), chemical composition assessed by XPS and thickness around 1 nm. The coatings lowered albumin adsorption and presented a decreased fibroblast, Streptococcus sanguinis and Lactobacillus salivarius adhesion. Immobilization of a cell adhesion peptide (RGD) presented a higher fibroblast adhesion and no alteration of the bacterial adhesion, giving three methods for the biofunctionalization of titanium for dental implants. The feasibility of each methodology is compared in terms of the process parameters in order to provide a guide for the election of the methodology.