Silicon-based hybrid luminescent/magnetic porous nanoparticles for biomedical applications

Silicon-based porous nanoparticles showing at the same time intense visible luminescence and magnetic response were fabricated. The hybrid luminescent/magnetic nanoparticles (hLMNPs) were fabricated by the electrodeposition of cobalt and iron into nanostructured porous silicon. These nanoparticles w...

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Bibliographic Details
Authors: Muñoz Noval, Álvaro, Sánchez-Vaquero, Vanessa, Torres-Costa, Vicente, Gallach, Daríoi, Manso-Silván, Miguel, García-Ruiz, Josefa P., Hernando-Pérez, M., Pablo, D. J. de, Martín-Palma, Raúl J.
Format: article
Publication Date:2011
Country:España
Institution:Universidad Complutense de Madrid (UCM)
Repository:Docta Complutense
Language:English
OAI Identifier:oai:docta.ucm.es:20.500.14352/117302
Online Access:https://hdl.handle.net/20.500.14352/117302
Access Level:Open access
Keyword:620.1
62-181.48
Porous silicon
Luminescence
Nanoparticle
Magnetic response
Functionalization
Biomedicine
Física de materiales
2211 Física del Estado Sólido
Description
Summary:Silicon-based porous nanoparticles showing at the same time intense visible luminescence and magnetic response were fabricated. The hybrid luminescent/magnetic nanoparticles (hLMNPs) were fabricated by the electrodeposition of cobalt and iron into nanostructured porous silicon. These nanoparticles were subsequently functionalized and internalized into cells. The hybrid behavior of the hLMNPs is a relevant feature for the development of research tools as nontoxic cellular tracker for progenitor cells and consequently able to be used in many strategies of cellular therapy. Additionally, the hLMNPs can be functionalized with various biomolecules that will endow them with new functionalities.