Silicon-based hybrid luminescent/magnetic porous nanoparticles for biomedical applications

Silicon-based porous nanoparticles showing at the same time intense visible luminescence and magnetic response were fabricated. The hybrid luminescent/magnetic nanoparticles (hLMNPs) were fabricated by the electrodeposition of cobalt and iron into nanostructured porous silicon. These nanoparticles w...

Descripción completa

Detalles Bibliográficos
Autores: Muñoz Noval, Álvaro, Sánchez-Vaquero, Vanessa, Torres-Costa, Vicente, Gallach, Daríoi, Manso-Silván, Miguel, García-Ruiz, Josefa P., Hernando-Pérez, M., Pablo, D. J. de, Martín-Palma, Raúl J.
Tipo de recurso: artículo
Fecha de publicación:2011
País:España
Institución:Universidad Complutense de Madrid (UCM)
Repositorio:Docta Complutense
Idioma:inglés
OAI Identifier:oai:docta.ucm.es:20.500.14352/117302
Acceso en línea:https://hdl.handle.net/20.500.14352/117302
Access Level:acceso abierto
Palabra clave:620.1
62-181.48
Porous silicon
Luminescence
Nanoparticle
Magnetic response
Functionalization
Biomedicine
Física de materiales
2211 Física del Estado Sólido
Descripción
Sumario:Silicon-based porous nanoparticles showing at the same time intense visible luminescence and magnetic response were fabricated. The hybrid luminescent/magnetic nanoparticles (hLMNPs) were fabricated by the electrodeposition of cobalt and iron into nanostructured porous silicon. These nanoparticles were subsequently functionalized and internalized into cells. The hybrid behavior of the hLMNPs is a relevant feature for the development of research tools as nontoxic cellular tracker for progenitor cells and consequently able to be used in many strategies of cellular therapy. Additionally, the hLMNPs can be functionalized with various biomolecules that will endow them with new functionalities.